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4,7-Dihydroxycoumarin (CID 54679630) - Compound BioActivity Data
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BioActivity Outcomes:
Active(3)
 
 
Inactive(673)
 
 
Inconclusive(9)
 
 
Unspecified(15)
 
 
Top Targets:
7tm 4(41)
 
 
Bcl-2 like(11)
 
 
alkPPc(10)
 
 
G-alpha(8)
 
 
 
Tryp SPc(7)
 
 
BioAssay Types:
Screening(469)
 
 
 
Confirmatory(191)
 
 
 
 
 
Literature(27)
 
 
 
 
BioActivity Types:
Potency(138)
 
 
 
 
 
IC50(44)
 
 
 
 
EC50(8)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 634    Data Row: 700   Total Pages: 35   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24824104]
Potency 14.1254qHTS of TDP-43 Inhibitors [AID652104, Type: confirmatory]TAR DNA-binding protein 43 [gi:20140568]
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2
[SID103207579]
IC50 38.85Inhibition of alpha-glucosidase using para-nitrophenyl substrate [AID541338, Type: Literature]
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3
[SID24824104]
Potency qHTS for Inhibitors of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) [AID652105, Type: confirmatory]Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [gi:18266879]
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4
[SID103207579]
IC50 300Inhibitory activity against 3'-processing of DNA by HIV-1 integrase [AID93533, Type: Literature]Integrase [gi:82312013]
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5
[SID103207579]
IC50 325Inhibitory activity against HIV-1 integrase [AID93680, Type: Literature]Integrase [gi:82312013]
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6
[SID103207579]
IC50 325Integration of DNA by HIV -1 integrase [AID91424, Type: Literature]Integrase [gi:82312013]
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7
[SID103207579]
IC50 400Inhibition of beta-glucosidase using salicin substrate [AID541494, Type: Literature]
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8
[SID24824104]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID103207579]
Inhibition of Aspergillus oryzae Beta-galactosidase at 400 uM [AID541342, Type: Literature]
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10
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as alpha-helix content at 0.5 uM bt circular dichroism method [AID541349, Type: Literature]
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11
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as alpha-helix content at 0.3 uM at circular dichroism method [AID541350, Type: Literature]
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12
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as beta-sheet content at 0.5 uM at circular dichroism method [AID541351, Type: Literature]
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13
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as beta-sheet content at 0.3 uM at circular dichroism method [AID541352, Type: Literature]
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14
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as beta-turn content at 0.5 uM at circular dichroism method [AID541353, Type: Literature]
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15
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as beta-turn content at 0.3 uM at circular dichroism method [AID541354, Type: Literature]
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16
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as random content at 0.5 uM at circular dichroism method [AID541355, Type: Literature]
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17
[SID103207579]
Effect on secondary structure of alpha-glucosidase assessed as random content at 0.3 uM at circular dichroism method [AID541356, Type: Literature]
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18
[SID103207579]
Inhibition of beta-glucosidase at 400 uM using salicin substrate [AID541263, Type: Literature]
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19
[SID24824104]
Potency 0.8913qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624287, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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20
[SID24824104]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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