STK565555
(CID
54679563
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
2
)
Inactive(
2
)
Unspecified(2)
Top Targets:
Ggt(
1
)
MarR(
1
)
BioAssay Types:
Literature(
4
)
BioActivity Types:
IC50(
2
)
Ki(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 6 Data Row: 6 Total Pages: 1
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
103287492
]
Active
Ki
11
Inhibition constant against Dihydrofolate reductase [AID
57403
, Type: Literature]
View
X
Row No.
1
Structure
Substance
SID
103287492
CID
54679563
Outcome
Active
Ki
11 [uM]
BioAssay
Inhibition constant against Dihydrofolate reductase
AID
57403
BioAssay type
Literature
Target
PubMed
12852950
Data Table
2
[SID
103287492
]
Active
IC50
48
Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductase [AID
57245
, Type: Literature]
View
X
Row No.
2
Structure
Substance
SID
103287492
CID
54679563
Outcome
Active
IC50
48 [uM]
BioAssay
Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductase
AID
57245
BioAssay type
Literature
Target
PubMed
12852950
Data Table
3
[SID
103287492
]
Unspecified
IC50
120
Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductase [AID
57244
, Type: Literature]
View
X
Row No.
3
Structure
Substance
SID
103287492
CID
54679563
Outcome
Unspecified
IC50
120 [uM]
BioAssay
Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductase
AID
57244
BioAssay type
Literature
Target
PubMed
12852950
Data Table
4
[SID
103287492
]
Unspecified
Ratio of IC50 in presence of 100 uM Dihydrofolate reductase [AID
57573
, Type: Literature]
View
X
Row No.
4
Structure
Substance
SID
103287492
CID
54679563
Outcome
Unspecified
BioAssay
Ratio of IC50 in presence of 100 uM Dihydrofolate reductase
AID
57573
BioAssay type
Literature
Target
PubMed
12852950
Data Table
5
[SID
92260029
]
Inactive
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID
492967
, Type: other]
gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:
47566732
]
View
X
Row No.
5
Structure
Substance
SID
92260029
CID
54679563
Outcome
Inactive
BioAssay
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis
AID
492967
BioAssay type
other
Target
gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:
47566732
]
PubMed
Data Table
6
[SID
92260029
]
Inactive
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID
602314
, Type: other]
MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:
151220867
]
View
X
Row No.
6
Structure
Substance
SID
92260029
CID
54679563
Outcome
Inactive
BioAssay
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein
AID
602314
BioAssay type
other
Target
MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:
151220867
]
PubMed
Data Table