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Warfarin (CID 54678486) - Compound BioActivity Data
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BioActivity Outcomes:
Active(40)
 
 
Inactive(863)
 
 
Inconclusive(60)
 
 
Unspecified(490)
 
 
Top Targets:
7tm 4(70)
 
 
 
NR LBD ER(25)
 
 
 
NR LBD AR(24)
 
 
 
 
NR LBD PPAR(23)
 
 
 
 
p450(22)
 
 
 
 
BioAssay Types:
Confirmatory(545)
 
 
 
 
 
Screening(361)
 
 
Literature(252)
 
 
 
 
 
Summary(63)
 
 
 
 
BioActivity Types:
Potency(438)
 
 
 
 
 
IC50(150)
 
 
 
 
Kd(9)
 
 
 
EC50(5)
 
 
 
Ki(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1220    Data Row: 1453   Total Pages: 73   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103532317]
IC50 0.00832Inhibition of pepsin from porcine gastric mucosa using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay [AID610484, Type: Literature]
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2
[SID103532317]
Kd 2Binding affinity to human serum albumin at 20 degC by isothermal titration calorimetry analysis [AID596704, Type: Literature]Serum albumin [gi:113576]
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3
[SID103532317]
IC50 2.2Inhibition of rat microsomal VKER [AID293981, Type: Literature]
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4
[SID103532317]
Kd 4.67735Binding affinity to human serum albumin by PAMPA method [AID327170, Type: Literature]Serum albumin [gi:113576]
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5
[SID103532317]
Kd 5.4Binding affinity to low-affinity binding site of human serum albumin at 20 degC by surface plasmon resonance assay [AID596696, Type: Literature]Serum albumin [gi:113576]
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6
[SID103532317]
Kd 9The compound was estimated for biosensor analysis [AID227925, Type: Literature]
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7
[SID144209380]
Ratio Potency (uM) 9.08587qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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8
[SID144209380]
Potency-Replicate_1 11.0078qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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9
[SID144206736]
Ratio Potency (uM) 11.1001qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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10
[SID103532317]
Kd 12Binding affinity to human serum albumin at 37 degC by surface plasmon resonance assay [AID596685, Type: Literature]Serum albumin [gi:113576]
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11
[SID144206736]
Potency-Replicate_1 13.3332qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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12
[SID144210849]
Ratio Potency (uM) 13.8006qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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13
[SID144206736]
Potency-Replicate_1 15.089qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway [AID743094, Type: confirmatory]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
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14
[SID103532317]
Kd 20Binding affinity to low-affinity binding site of rat serum albumin at 20 degC by surface plasmon resonance assay [AID596699, Type: Literature]Serum albumin [gi:124028612]
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15
[SID103532317]
Ki 20Binding affinity towards cytochrome P450 2C9 [AID54410, Type: Literature]
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16
[SID144206736]
Ratio Potency (uM) 21.1317qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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17
[SID103532317]
IC50 24.59Inhibition of recombinant type 8 subtilisin using Arg-Glu-(EDANS)- Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys-(DALBCYL)-Arg fluorogenic substrate preincubated for 1 hr measured after 1 hr at 1 min interval by fluorescence assay [AID610485, Type: Literature]
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18
[SID26754489]
Potency 39.8107qHTS assay for small molecule activators of the p53 signaling pathway [AID651743, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
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19
[SID144210849]
Potency-Replicate_1 48.5577qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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20
[SID144210849]
Ratio Potency (uM) 54.4827qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
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