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SMR000111185 (CID 54676686) - Compound BioActivity Data
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BioActivity Outcomes:
Active(30)
 
 
Inactive(800)
 
 
Inconclusive(38)
 
 
Unspecified(1)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(21)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(9)
 
 
BioAssay Types:
Screening(577)
 
 
 
 
Confirmatory(259)
 
 
 
 
 
Literature(16)
 
 
 
BioActivity Types:
Potency(167)
 
 
 
 
IC50(56)
 
 
 
EC50(17)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 798    Data Row: 869   Total Pages: 44   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7976488]
EC50 6.341Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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2
[SID7976488]
EC50 8.577Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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3
[SID7976488]
IC50 8.62Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624317, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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4
[SID103473020]
IC50 16Inhibition of strand transfer catalytic activity HIV1 integrase [AID257141, Type: Literature]Integrase [gi:82312013]
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5
[SID103473020]
IC50 16Inhibition of HIV1 integrase strand transfer activity by PAGE [AID394563, Type: Literature]
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6
[SID7976488]
EC50 28.584Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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7
[SID103473020]
IC50 40Inhibition of HIV1 integrase 3' processing activity by PAGE [AID394562, Type: Literature]
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8
[SID103473020]
IC50 40Inhibition of 3'-processing catalytic activity HIV1 integrase [AID257140, Type: Literature]Integrase [gi:82312013]
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9
[SID7976488]
IC50_Mean 61.15Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 [AID651709, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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10
[SID7976488]
uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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11
[SID7976488]
Single concentration confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624309, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
View
12
[SID7976488]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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13
[SID7976488]
Validation (re-confirmation) assay for identification of compounds that inhibit KCNQ1 potassium channels [AID588353, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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14
[SID7976488]
Primary cell-based high-throughput screening assay for identification of compounds that inhibit KCNQ1 potassium channels [AID2642, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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15
[SID7976488]
Specificity screen against KCNQ1/KCNE1 for identification of compounds that inhibit KCNQ1 potassium channels [AID652147, Type: screening]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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16
[SID7976488]
Specificity screen against KCNQ2 for identification of compounds that inhibit KCNQ1 potassium channels [AID651746, Type: screening]potassium voltage-gated channel subfamily KQT member 2 [Rattus norvegicus] [gi:18959272]
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17
[SID7976488]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
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18
[SID7976488]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
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19
[SID7976488]
Chemical Genetic Screen to Identify Inhibitors of Mitochondrial Fusion - Primary Screen [AID1362, Type: screening]
View
20
[SID7976488]
TNFalpha Induced E-Selectin Expression - Primary screen [AID487, Type: screening]
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