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CHEMBL197014 (CID 54676686) - Compound BioActivity Data
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BioActivity Outcomes:
Active(30)
 
 
Inactive(800)
 
 
Inconclusive(38)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(48)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(12)
 
 
Tryp SPc(9)
 
 
G-alpha(8)
 
 
 
BioAssay Types:
Screening(577)
 
 
 
 
Confirmatory(259)
 
 
 
 
 
Literature(16)
 
 
 
BioActivity Types:
Potency(167)
 
 
 
 
IC50(56)
 
 
 
EC50(17)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 798    Data Row: 869   Total Pages: 44   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7976488]
EC50 6.341Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
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2
[SID7976488]
EC50 8.577Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
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3
[SID7976488]
IC50 8.62Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay [AID624317, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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4
[SID103473020]
IC50 16Inhibition of strand transfer catalytic activity HIV1 integrase [AID257141, Type: Literature]Integrase [gi:82312013]
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5
[SID103473020]
IC50 16Inhibition of HIV1 integrase strand transfer activity by PAGE [AID394563, Type: Literature]
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6
[SID7976488]
EC50 28.584Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
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7
[SID103473020]
IC50 40Inhibition of 3'-processing catalytic activity HIV1 integrase [AID257140, Type: Literature]Integrase [gi:82312013]
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8
[SID103473020]
IC50 40Inhibition of HIV1 integrase 3' processing activity by PAGE [AID394562, Type: Literature]
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9
[SID7976488]
IC50_Mean 61.15Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 [AID651709, Type: confirmatory]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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10
[SID7976488]
uHTS identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay [AID485273, Type: screening]ubiquitin-conjugating enzyme E2 N [Homo sapiens] [gi:4507793]
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11
[SID7976488]
Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators [AID449, Type: screening]sphingosine 1-phosphate receptor 1 [Homo sapiens] [gi:13027636]
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12
[SID7976488]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]Breast cancer type 1 susceptibility protein [gi:728984]
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13
[SID7976488]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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14
[SID7976488]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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15
[SID7976488]
Single concentration confirmation of inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay. [AID504668, Type: screening]BRCA1-associated RING domain protein 1 [gi:116241265]
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16
[SID7976488]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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17
[SID7976488]
Single concentration confirmation of uHTS for Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID489028, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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18
[SID7976488]
HTS for small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress [AID2732, Type: screening]DNA damage-inducible transcript 3 protein [Mus musculus] [gi:160707929]
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19
[SID7976488]
Specificity screen against KCNQ1/KCNE1 for identification of compounds that inhibit KCNQ1 potassium channels [AID652147, Type: screening]potassium voltage-gated channel subfamily E member 1 [Homo sapiens] [gi:189095237]
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20
[SID7976488]
uHTS identification of inhibitors of NadD in a Colorimetric assay [AID602399, Type: screening]hypothetical protein SA1422 [Staphylococcus aureus subsp. aureus N315] [gi:15927174]
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