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BioActivity Data for Compound meclocycline (CID 54676538)

BioActivity Outcomes:
Active(64)
 
 
Inactive(75)
 
 
Inconclusive(36)
 
 
Unspecified(13)
 
 
Top Targets:
NR LBD AR(7)
 
 
 
NR LBD ER(7)
 
 
 
NR LBD GR(4)
 
 
 
NR LBD TR(3)
 
 
crotonase-lik..(2)
 
 
BioAssay Types:
Literature(67)
 
 
 
 
Confirmatory(50)
 
 
 
 
Summary(15)
 
 
 
Screening(7)
 
 
BioAssay Categories:
In vitro(3)
 
 
 
In vivo(2)
 
 
Biochemical(6)
 
 
 
 
Toxicity(15)
 
 
 
 
ADME(2)
 
 
Cell-based(5)
 
 
 
Organism-base..(2)
 
 
BioActivity Types:
Potency(63)
 
 
 
 
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 124    Data Row: 188   Total Pages: 10   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103567316]
IC50 0.25Inhibition of synthetic amyloid beta-42 oligomerization by ELISA [AID322955, Type: Literature]
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2
[SID144204345]
Potency 11.3743qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]50S ribosomal protein L36 2 [gi:110816409]
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4
[SID103567316]
Inhibition of synthetic amyloid beta-42 fibrillation by light scattering analysis relative to control [AID322958, Type: Literature]
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5
[SID8149716]
Cellular toxicity caused by inducible expressing of N-terminal huntingtin with expanded ployglutamine repeat (Htt-N63-148Q) in PC12 cells (ROSShtt) [AID1590, Type: other]
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6
[SID8149716]
Screen for compounds that inhibit in vitro mutant huntingtin aggregation (QA1) [AID1584, Type: other]
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7
[SID103567316]
Binding affinity to amyloid beta (1 to 42) oligomers by change in fluorescence at 100 uM after 10 mins [AID475505, Type: Literature]
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8
[SID103567316]
Binding affinity to amyloid beta (1 to 42) fibrils by change in fluorescence at 100 uM after 10 mins [AID475504, Type: Literature]
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9
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S21 [gi:56405133]
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10
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]50S ribosomal protein L25 [gi:60393658]
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11
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S2 [gi:62288920]
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12
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S12 [gi:62288954]
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13
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S19 [gi:62288960]
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14
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S20 [gi:62288964]
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15
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S3 [gi:62288973]
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16
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S4 [gi:62288978]
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17
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]30S ribosomal protein S5 [gi:62288981]
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18
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]50S ribosomal protein L1 [gi:67471900]
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19
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]50S ribosomal protein L10 [gi:67471992]
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20
[SID103567316]
Bacterial 70S ribosome inhibitor [AID742681, Type: Literature]50S ribosomal protein L11 [gi:67471996]
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