Bookmark and Share

BioActivity Data for Compound Acenocoumarol (CID 54676537)

BioActivity Outcomes:
Active(7)
 
 
Inactive(912)
 
 
Inconclusive(13)
 
 
Unspecified(38)
 
 
Top Targets:
7tm 4(46)
 
 
Bcl-2 like(12)
 
 
NR LBD PPAR(12)
 
 
 
 
alkPPc(12)
 
 
Esterase lipa..(8)
 
 
BioAssay Types:
Screening(574)
 
 
 
 
 
Confirmatory(290)
 
 
 
 
 
Literature(57)
 
 
 
 
Summary(28)
 
 
 
 
BioAssay Categories:
In vitro(1)
 
 
In vivo(2)
 
 
 
Biochemical(139)
 
 
 
Toxicity(33)
 
 
 
ADME(13)
 
 
Cell-based(156)
 
 
Organism-base..(15)
 
 
BioActivity Types:
Potency(248)
 
 
 
 
 
IC50(45)
 
 
 
 
EC50(7)
 
 
AC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 885    Data Row: 970   Total Pages: 49   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103532358]
IC50 0.77Inhibition of rat microsomal VKER [AID293981, Type: Literature]
View
2
[SID144203981]
Potency-Replicate_1 7.1669qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
View
3
[SID144203981]
Ratio Potency (uM) 8.35601qHTS assay for small molecule disruptors of the mitochondrial membrane potential: Summary [AID720637, Type: summary]
View
4
[SID17385821]
Non-Nucleoside Inhibitor of Measles Virus RNA-Dependent RNA Polymerase Complex Activity HTS Single Point (MLSMR Library) [AID841, Type: screening]
View
5
[SID48415501]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
View
6
[SID17385821]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
View
7
[SID144203981]
Ratio Potency (uM) qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor gamma (PPARg) signaling pathway: Summary [AID743140, Type: summary]peroxisome proliferator activated receptor gamma [Homo sapiens] [gi:216409692]
View
8
[SID103532358]
Cirrhosis, proven histopathologically. Value is number of references indexed. [column 'CIRRH' in source] [AID1079939, Type: Literature]
View
9
[SID103532358]
Choleostatic liver toxicity, either proven histopathologically or where the ratio of maximal ALT or AST activity above normal to that of Alkaline Phosphatase is < 2 (see ACUTE). Value is number of references indexed. [column 'CHOLE' in source] [AID1079936, Type: Literature]
View
10
[SID103532358]
Times to onset, minimal and maximal, observed in the indexed observations. [column 'DELAI' in source] [AID1079948, Type: Literature]
View
11
[SID170465636]
AC50 (uM) qHTS Assay for Identifying Compounds that block Entry of Ebola Virus, Screen 2 green channel [AID1117298, Type: confirmatory]
View
12
[SID103532358]
Comments (NB not yet translated). [column 'COMMENTAIRES' in source] [AID1079947, Type: Literature]
View
13
[SID103532358]
Proposed mechanism(s) of liver damage. [column 'MEC' in source] [AID1079949, Type: Literature]
View
14
[SID103532358]
Drug Induced Liver Injury Prediction System (DILIps) validation dataset; compound DILI positive/negative as observed in Pfizer data [AID625295, Type: Literature]
View
15
[SID103532358]
Liver damage due to vascular disease: peliosis hepatitis, hepatic veno-occlusive disease, Budd-Chiari syndrome. Value is number of references indexed. [column 'VASC' in source] [AID1079941, Type: Literature]
View
16
[SID103532358]
Steatosis, proven histopathologically. Value is number of references indexed. [column 'STEAT' in source] [AID1079942, Type: Literature]
View
17
[SID103532358]
Malignant tumor, proven histopathologically. Value is number of references indexed. [column 'T.MAL' in source] [AID1079943, Type: Literature]
View
18
[SID103532358]
Moderate liver toxicity, defined via clinical-chemistry results: ALT or AST serum activity 6 times the normal upper limit (N) or alkaline phosphatase serum activity of 1.7 N. Value is number of references indexed. [column 'BIOL' in source] [AID1079931, Type: Literature]
View
19
[SID103532358]
Chronic liver disease either proven histopathologically, or through a chonic elevation of serum amino-transferase activity after 6 months. Value is number of references indexed. [column 'CHRON' in source] [AID1079938, Type: Literature]
View
20
[SID103532358]
Benign tumor, proven histopathologically. Value is number of references indexed. [column 'T.BEN' in source] [AID1079944, Type: Literature]
View