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CHEMBL1603825 (CID 54676535) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(76)
 
 
Inconclusive(9)
 
 
Unspecified(2)
 
 
Top Targets:
PLDc mTdp1 2(3)
 
 
P53(2)
 
 
NR LBD TR(2)
 
 
NR LBD ROR li..(2)
 
 
Menin(2)
 
 
BioAssay Types:
Confirmatory(68)
 
 
 
 
Screening(13)
 
 
 
Literature(6)
 
 
 
BioActivity Types:
Potency(66)
 
 
 
 
IC50(2)
 
 
Ki(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 87    Data Row: 92   Total Pages: 5   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID174510284]
Ki 0.56Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977604, Type: Literature]
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2
[SID174510284]
Ki 0.59Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977601, Type: Literature]
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3
[SID174510284]
IC50 0.74131pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977603, Type: Literature]
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4
[SID174510284]
IC50 1.07152pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977600, Type: Literature]
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5
[SID26749607]
Potency 79.4328Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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6
[SID174510284]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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7
[SID174510284]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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8
[SID26749607]
Potency 19.9526qHTS Assay for Activators of Cytochrome P450 3A4 [AID885, Type: confirmatory]cytochrome P450 3A4 isoform 1 [Homo sapiens] [gi:13435386]
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9
[SID26749607]
Potency 22.3872qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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10
[SID26749607]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
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11
[SID26749607]
Potency A Quantitative High throughput Screen to Identify Chemical Modulators of PINK1 Expression [AID624263, Type: confirmatory]Parkin [Homo sapiens] [gi:3063388]
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12
[SID26749607]
Potency A Quantitative High throughput Screen to Identify Chemical Modulators of PINK1 Expression [AID624263, Type: confirmatory]PINK1 [Homo sapiens] [gi:37183032]
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13
[SID85787089]
Fluorescence Cell-Based Primary HTS to Identify Reactive Oxygen Species Inducers in Cancer Cells Measured in Cell-Based System Using Plate Reader and Imaging Combination - 2044-01_Activator_SinglePoint_HTS_Activity [AID624156, Type: screening]
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14
[SID26749607]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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15
[SID26749607]
Potency qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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16
[SID26749607]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
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17
[SID26749607]
Potency qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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18
[SID26749607]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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19
[SID26749607]
Potency qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: Venus Reporter Primary qHTS [AID720580, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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20
[SID26749607]
Potency qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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