Bookmark and Share
NSC686389 (CID 54676522) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(40)
 
 
Inactive(606)
 
 
Inconclusive(41)
 
 
Unspecified(10)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(17)
 
 
TRP 2(10)
 
 
 
G-alpha(8)
 
 
 
Bcl-2 like(8)
 
 
BioAssay Types:
Screening(401)
 
 
 
 
Confirmatory(254)
 
 
 
 
 
Literature(22)
 
 
 
 
BioActivity Types:
Potency(145)
 
 
 
 
 
IC50(43)
 
 
 
 
EC50(13)
 
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 634    Data Row: 697   Total Pages: 35   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24802850]
IC50 3.67Dose response confirmation of small molecule inhibitors of the thioesterase domain of fatty acid synthase via a kinetic, fluorescence intensity assay [AID624326, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
View
2
[SID24802850]
IC50 4.65Dose response confirmation of uHTS inhibitor hits of the thioesterase domain of fatty acid synthase via a fluorescence intensity assay [AID624327, Type: confirmatory]fatty acid synthase [Homo sapiens] [gi:41872631]
View
3
[SID24802850]
EC50 6.297Luminescence Microorganism-Based Dose Confirmation HTS to Identify Inhibitors of Streptokinase Promotor Activity [AID1902, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
View
4
[SID24802850]
IC50 7.83026Dose Response Confirmation for Calpain Inhibitors [AID1420, Type: confirmatory]calpain II, partial [Sus scrofa] [gi:1628587]
View
5
[SID24802850]
EC50 8.091Luminescence Microorganism-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to SK(-)GAS Group A Streptococcus [AID1900, Type: confirmatory]
View
6
[SID103286771]
IC50 12Integration of DNA by HIV -1 integrase [AID91424, Type: Literature]Integrase [gi:82312013]
View
7
[SID24802850]
EC50 13.358Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression [AID1914, Type: confirmatory]streptokinase A [Streptococcus pyogenes M1 GAS] [gi:15675770]
View
8
[SID24802850]
IC50 13.8uHTS fluorescence assay for the identification of Human Immunodeficiency Virus Fusion Inhibitors. [AID1986, Type: confirmatory]envelope glycoprotein [Human immunodeficiency virus 1] [gi:45357394]
View
9
[SID24802850]
Potency 19.0115qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
10
[SID24802850]
Potency 19.9526qHTS for Inhibitors of Polymerase Eta [AID588591, Type: confirmatory]DNA polymerase eta [Homo sapiens] [gi:5729982]
View
11
[SID24802850]
Potency 22.3872qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
View
12
[SID24802850]
Potency 26.5813Confirmation Assay for Inhibitors of Human Galactokinase (GALK) [AID2015, Type: confirmatory]galactokinase [Homo sapiens] [gi:4503895]
View
13
[SID24802850]
IC50 34.01Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) [AID1445, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:124512980]
View
14
[SID24802850]
Potency 39.8107qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
15
[SID24802850]
Magi EC50 50A Cell Based Assay for the Identification of Lead Compounds with Inhibitory Activity against HIV-1 Fusion (CCR5 Tropic HIV-1 Fusion Inhibition Assay) - Cytotoxicity Counter Screen - Dose Response [AID2286, Type: confirmatory]
View
16
[SID24802850]
Potency 50.1187qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen [AID720709, Type: confirmatory]Rap guanine nucleotide exchange factor 3 [gi:317373593]
View
17
[SID24802850]
Potency 50.1187qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
View
18
[SID24802850]
Potency 50.1187qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen [AID720708, Type: confirmatory]Rap guanine nucleotide exchange factor 4 [gi:32171491]
View
19
[SID24802850]
Potency 56.2341qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
View
20
[SID24802850]
EC50 101.929Luminescence Microorganism-Based Dose Response HTS to Identify Compounds Cytotoxic to Streptococcus [AID1915, Type: confirmatory]
View