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Dicumarol (CID 54676038) - Compound BioActivity Data
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BioActivity Outcomes:
Active(57)
 
 
Inactive(315)
 
 
Inconclusive(72)
 
 
Unspecified(393)
 
 
Top Targets:
7TM GPCR Srsx(32)
 
 
 
7TM GPCR Srx(32)
 
 
p450(29)
 
 
 
 
 
NR LBD ER(11)
 
 
 
 
 
Flavodoxin 2(10)
 
 
BioAssay Types:
Confirmatory(471)
 
 
 
 
 
Literature(165)
 
 
 
 
Summary(24)
 
 
 
 
Screening(19)
 
 
BioActivity Types:
IC50(261)
 
 
 
 
Potency(227)
 
 
 
 
 
Ki(7)
 
 
 
EC50(4)
 
 
Kd(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 521    Data Row: 837   Total Pages: 42   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103224818]
IC50 0.0026Inhibition of human recombinant NQO1 [AID441648, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
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2
[SID103532383]
IC50 0.0026Inhibition of human recombinant NQO1 [AID441648, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
3
[SID103224818]
IC50 0.005Inhibition of human recombinant NQO1 [AID304251, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
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4
[SID103532383]
IC50 0.005Inhibition of human recombinant NQO1 [AID304251, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
5
[SID11112184]
Potency 0.0251qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9 [AID883, Type: confirmatory]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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6
[SID103224818]
Ki 0.039Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis [AID769725, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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7
[SID103532383]
Ki 0.039Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysis [AID769725, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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8
[SID103224818]
IC50 0.3DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
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9
[SID103532383]
IC50 0.3DRUGMATRIX: CYP450, 2C9 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) [AID625248, Type: confirmatory]Cytochrome P450 2C9 [gi:6686268]
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10
[SID103224818]
IC50 0.404Inhibition of human recombinant NQO1 in presence of BSA [AID441649, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
11
[SID103532383]
IC50 0.404Inhibition of human recombinant NQO1 in presence of BSA [AID441649, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
12
[SID103224818]
IC50 0.45Inhibition of human recombinant NQO1 in presence of BSA [AID304252, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
13
[SID103532383]
IC50 0.45Inhibition of human recombinant NQO1 in presence of BSA [AID304252, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
14
[SID103224818]
IC50 0.45Inhibition of human recombinant NQO1 [AID277029, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
15
[SID103532383]
IC50 0.45Inhibition of human recombinant NQO1 [AID277029, Type: Literature]NAD(P)H dehydrogenase [quinone] 1 [gi:118607]
View
16
[SID144203908]
Potency-Replicate_1 0.5074qHTS assay for small molecule agonists of the p53 signaling pathway - cell viability [AID651633, Type: confirmatory]
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17
[SID103532383]
Ki 0.6Binding affinity was measured on Cytochrome P450 2C9 [AID54403, Type: Literature]
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18
[SID103224818]
Ki 0.6Binding affinity was measured on Cytochrome P450 2C9 [AID54403, Type: Literature]
View
19
[SID144203908]
Potency-Replicate_1 0.6388qHTS assay for small molecule agonists of the p53 signaling pathway [AID651631, Type: confirmatory]Cellular tumor antigen p53 [gi:269849759]
View
20
[SID144203908]
Ratio Potency (uM) 1.13588qHTS assay for small molecule agonists of the p53 signaling pathway: Summary [AID720552, Type: summary]Cellular tumor antigen p53 [gi:269849759]
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