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UPCMLD00WJUN1360 (CID 5461521) - Compound BioActivity Data
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BioActivity Outcomes:
Active(44)
 
 
Inactive(335)
 
 
Inconclusive(26)
 
 
Top Targets:
7TM GPCR Srx(11)
 
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(9)
 
 
HSF(7)
 
 
 
G-alpha(6)
 
 
 
BioAssay Types:
Screening(250)
 
 
 
 
Confirmatory(143)
 
 
 
 
Literature(2)
 
 
BioActivity Types:
Potency(81)
 
 
 
 
IC50(35)
 
 
 
 
EC50(15)
 
 
 
 
AC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 378    Data Row: 405   Total Pages: 21   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID24708047]
IC50 0.51177Luminescence-based dose response cell-based high throughput screening assay for cytotoxic compounds using the IEC-6 intestinal epithelial cell line. [AID1972, Type: confirmatory]
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2
[SID24708047]
EC50_uM 0.536Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity [AID435010, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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3
[SID24708047]
AC50_uM 0.9789Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity [AID449749, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
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4
[SID24708047]
EC50_uM 1.016Fluorescence Cell-Free Homogeneous Counter Screen to Identify Inhibitors of GFP Chromophore Formation [AID434968, Type: confirmatory]recombinase A [Mycobacterium tuberculosis H37Rv] [gi:15609874]
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5
[SID24708047]
Potency 1.4716Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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6
[SID24708047]
AC50_uM 1.539Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity [AID449750, Type: confirmatory]replicative DNA helicase [Mycobacterium tuberculosis H37Rv] [gi:15607200]
View
7
[SID24708047]
Potency 1.6511Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
8
[SID24708047]
EC50 1.88Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of of 5'UTR Stem-Loop Driven Alpha-Synuclein mRNA Translation in H4 Neuroglioblastoma Cells [AID1988, Type: confirmatory]
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9
[SID24708047]
EC50 1.986Luminescence Cell-Based Dose Response HTS to Identify Inhibitors of Luciferase Translation or Activity in H4 Neuroglioblastoma Cells [AID1990, Type: confirmatory]
View
10
[SID103023269]
AC50_uM 2.28HSF-1 induced GFP reporter and Doxycycline induced RFP reporter Measured in Cell-Based System Using Plate Reader - 2038-03_Inhibitor_Dose_DryPowder_Activity [AID602269, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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11
[SID103023269]
AC50_uM 2.37Heat Shock Factor-1 (HSF-1) Luciferase Reporter Measured in Cell-Based System Using Plate Reader - 2038-01_Inhibitor_Dose_DryPowder_Activity [AID602268, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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12
[SID24708047]
Potency 2.9093qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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13
[SID24708047]
Potency 4.1095qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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14
[SID24708047]
AC50_uM 5.567HSF-1 induced GFP reporter and Doxycycline induced RFP reporter Measured in Cell-Based System Using Plate Reader - 2038-03_Inhibitor_DoseNoFile_CherryPick_Activity_Set3 [AID493083, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
View
15
[SID24708047]
EC50 6.808Luminescence Cell-Based Dose Response HTS to Identify Inhibitors of 5'UTR Stem-Loop Driven Prion Protein mRNA Translation in H4 Neuroglioblastoma Cells [AID1994, Type: confirmatory]
View
16
[SID24708047]
Potency 10qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
17
[SID24708047]
Potency 10.3225A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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18
[SID24708047]
EC50 10.366Luminescence Cell-Based Dose Confimation HTS to Identify Inhibitors of Heat Shock Factor 1 (HSF1) [AID2382, Type: confirmatory]Hsf1 protein [Mus musculus] [gi:62740231]
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19
[SID24708047]
Potency 11.5821qHTS Assay for Lipid Storage Modulators in Drosophila S3 Cells [AID2685, Type: confirmatory]
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20
[SID24708047]
Potency 25.1189qHTS Assay for Inhibitors of Bloom's syndrome helicase (BLM) [AID2528, Type: confirmatory]Bloom syndrome protein isoform 1 [Homo sapiens] [gi:4557365]
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