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(S)-[11C]-Ibuprofen (CID 54586625) - Compound BioActivity Data
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BioActivity Outcomes:
Active(5)
 
 
Inactive(1)
 
 
Unspecified(7)
 
 
BioAssay Types:
Literature(13)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 13    Data Row: 13   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131285540]
Biodistribution in LPS treated BALB/c mouse anti-collagen antibody-induced arthritis model arthritic joints at 9 to 12 MBq, iv after 30 mins by PET analysis [AID598058, Type: Literature]
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2
[SID131285540]
Biodistribution in mouse liver at 9 to 12 MBq, iv after 30 mins by PET analysis [AID598062, Type: Literature]
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3
[SID131285540]
Biodistribution in mouse kidney at 9 to 12 MBq, iv after 30 mins by PET analysis [AID598063, Type: Literature]
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4
[SID131285540]
Biodistribution in mouse bladder at 9 to 12 MBq, iv after 30 mins by PET analysis [AID598064, Type: Literature]
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5
[SID131285540]
Biodistribution in mouse cerebrum at 9 to 12 MBq, iv after 30 mins by PET analysis [AID598061, Type: Literature]
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6
[SID131285540]
Drug level in mouse plasma assessed as [11C]-ibuprofen level at 70 to 125 MBq, iv after 30 mins by HPLC analysis [AID598068, Type: Literature]
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7
[SID131285540]
Drug level in mouse plasma assessed as fraction of metabolites level at 70 to 125 MBq, iv after 30 mins by HPLC analysis [AID598065, Type: Literature]
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8
[SID131285540]
Drug level in mouse plasma assessed as (R)-[11C]-ibuprofen level at 70 to 125 MBq, iv after 30 mins by HPLC analysis [AID598066, Type: Literature]
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9
[SID131285540]
Drug level in mouse plasma assessed as (S)-[11C]-ibuprofen level at 70 to 125 MBq, iv after 30 mins by HPLC analysis [AID598067, Type: Literature]
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10
[SID131285540]
Biodistribution in LPS treated BALB/c mouse anti-collagen antibody-induced arthritis model ankle of hindlimb at 9 to 12 MBq, iv after 30 mins by PET analysis relative to normal mouse [AID598059, Type: Literature]
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11
[SID131285540]
Drug level in mouse plasma at 70 to 125 MBq, iv after 30 mins by HPLC analysis [AID597588, Type: Literature]
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12
[SID131285540]
Drug level in mouse plasma assessed as radioactivity of [11C]-ibuprofen at 70 to 125 MBq, iv after 30 mins by HPLC analysis [AID597589, Type: Literature]
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13
[SID131285540]
Biodistribution in LPS treated BALB/c mouse anti-collagen antibody-induced arthritis model heart at 9 to 12 MBq, iv after 30 mins by PET analysis [AID598060, Type: Literature]
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