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CHEMBL1783654 (CID 54581404) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Top Targets:
NR LBD RAR(3)
 
 
NR LBD RXR li..(1)
 
 
BioAssay Types:
Literature(4)
 
 
BioActivity Types:
IC50(3)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131274917]
IC50 Antagonist activity at yeast GAL4 fused mouse RARalpha ligand binding domain expressed in HeLa cells assessed as inhibition of TTNPB-induced receptor transactivation by luciferase reporter gene assay [AID600525, Type: Literature]Retinoic acid receptor alpha [gi:133484]
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2
[SID131274917]
IC50 Antagonist activity at yeast GAL4 fused mouse RARbeta ligand binding domain expressed in HeLa cells assessed as inhibition of TTNPB-induced receptor transactivation by luciferase reporter gene assay [AID599098, Type: Literature]Retinoic acid receptor beta [gi:133494]
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3
[SID131274917]
Agonist activity at yeast GAL4 fused human RXRbeta ligand binding domain expressed in HeLa cells assessed as receptor transactivation by luciferase reporter gene assay [AID600524, Type: Literature]Retinoic acid receptor RXR-beta [gi:1350911]
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4
[SID131274917]
IC50 Antagonist activity at yeast GAL4 fused mouse RARgamma ligand binding domain expressed in HeLa cells assessed as inhibition of TTNPB-induced receptor transactivation by luciferase reporter gene assay [AID599099, Type: Literature]Retinoic acid receptor gamma [gi:166899090]
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