CHEMBL1771107 (CID 54580905) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(9)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srx(3)
 
 
7TM GPCR Srsx(1)
 
 
BioAssay Types:
Literature(14)
 
 
 
BioActivity Types:
Ki(8)
 
 
EC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 14    Data Row: 14   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131273733]
Ki 0.00025Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells [AID594007, Type: Literature]D(3) dopamine receptor [gi:1169206]
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2
[SID131273733]
Ki 0.00025Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells [AID594007, Type: Literature]D(3) dopamine receptor [gi:1169206]
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3
[SID131273733]
Ki 0.00025Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells [AID594007, Type: Literature]D(3) dopamine receptor [gi:1169206]
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4
[SID131273733]
Ki 0.00025Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cells [AID594007, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
5
[SID131273733]
EC50 0.0033Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation [AID594018, Type: Literature]D(3) dopamine receptor [gi:1169206]
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6
[SID131273733]
EC50 0.0033Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation [AID594018, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
7
[SID131273733]
EC50 0.0033Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation [AID594018, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
8
[SID131273733]
EC50 0.0033Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation [AID594018, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
9
[SID131273733]
Ki 0.0034Displacement of [3H]Spiperone from human dopamine D4.4 receptor expressed in CHO cells [AID594008, Type: Literature]
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10
[SID131273733]
Ki 0.0054Displacement of [3H]Prazosin from pig adrenergic alpha1 receptor [AID594011, Type: Literature]
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11
[SID131273733]
Ki 0.015Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells [AID594006, Type: Literature]D(2) dopamine receptor [gi:118206]
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12
[SID131273733]
Ki 0.015Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells [AID594006, Type: Literature]D(2) dopamine receptor [gi:118206]
View
13
[SID131273733]
Ki 0.015Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells [AID594006, Type: Literature]D(2) dopamine receptor [gi:118206]
View
14
[SID131273733]
Ki 0.015Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells [AID594006, Type: Literature]D(2) dopamine receptor [gi:118206]
View
15
[SID131273733]
Ki 0.015Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cells [AID594006, Type: Literature]D(2) dopamine receptor [gi:118206]
View
16
[SID131273733]
Ki 0.038Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells [AID594005, Type: Literature]D(2) dopamine receptor [gi:118206]
View
17
[SID131273733]
Ki 0.038Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells [AID594005, Type: Literature]D(2) dopamine receptor [gi:118206]
View
18
[SID131273733]
Ki 0.038Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells [AID594005, Type: Literature]D(2) dopamine receptor [gi:118206]
View
19
[SID131273733]
Ki 0.038Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells [AID594005, Type: Literature]D(2) dopamine receptor [gi:118206]
View
20
[SID131273733]
Ki 0.038Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cells [AID594005, Type: Literature]D(2) dopamine receptor [gi:118206]
View
21
[SID131273733]
Ki 0.038Displacement of [3H]WAY-100635 from pig 5-HT1A receptor [AID594009, Type: Literature]
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22
[SID131273733]
Ki 0.33Displacement of [3H]Ketanserin from pig 5-HT2 receptor [AID594010, Type: Literature]5-hydroxytryptamine receptor 2A [gi:1703009]
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23
[SID131273733]
Ki 0.64Displacement of [3H]SCH-23390 from dopamine D1 receptor in pig striatal membranes [AID594004, Type: Literature]D(1A) dopamine receptor [gi:1706296]
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24
[SID131273733]
 Selectivity ratio of Ki for human dopamine D3 receptor over Ki for pig dopamine D1 receptor [AID594012, Type: Literature]
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25
[SID131273733]
 Selectivity ratio of Ki for human dopamine D3 receptor over Ki for pig dopamine D2 long receptor [AID594013, Type: Literature]
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26
[SID131273733]
 Selectivity ratio of Ki for human dopamine D3 receptor over Ki for pig dopamine D2 short receptor [AID594014, Type: Literature]
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27
[SID131273733]
 Selectivity ratio of Ki for human dopamine D3 receptor over Ki for human dopamine D4 receptor [AID594016, Type: Literature]
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28
[SID131273733]
 Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation relative to quinpirole [AID594017, Type: Literature]D(3) dopamine receptor [gi:1169206]
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29
[SID131273733]
 Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation relative to quinpirole [AID594017, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
30
[SID131273733]
 Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation relative to quinpirole [AID594017, Type: Literature]D(3) dopamine receptor [gi:1169206]
View
31
[SID131273733]
 Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporation relative to quinpirole [AID594017, Type: Literature]D(3) dopamine receptor [gi:1169206]
View