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3-ethyl-7-hydroxy-4-methylchromen-2-one (CID 5420889) - Compound BioActivity Data
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BioActivity Outcomes:
Unspecified(11)
 
 
Top Targets:
RHD-n RelA(1)
 
 
BioAssay Types:
Literature(11)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 11    Data Row: 11   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134435028]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced NO production at 10 uM by Griess reaction [AID613464, Type: Literature]
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2
[SID134435028]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced NO production at 100 uM by Griess reaction [AID613465, Type: Literature]
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3
[SID134435028]
Inhibition of LPS-stimulated iNOS protein expression in mouse J774 cells at 10 uM by RT-PCR analysis [AID613466, Type: Literature]
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4
[SID134435028]
Inhibition of LPS-stimulated iNOS protein expression in mouse J774 cells at 100 uM by RT-PCR analysis [AID613467, Type: Literature]
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5
[SID134435028]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced IL-6 production at 10 uM by ELISA [AID613470, Type: Literature]
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6
[SID134435028]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced IL-6 production at 100 uM by ELISA [AID613471, Type: Literature]
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7
[SID134435028]
Inhibition of LPS-stimulated COX2 protein expression in mouse J774 cells at 10 uM by chemiluminescence assay [AID613472, Type: Literature]
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8
[SID134435028]
Inhibition of LPS-stimulated COX2 protein expression in mouse J774 cells at 100 uM by chemiluminescence assay [AID613473, Type: Literature]
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9
[SID134435028]
Cytotoxicity against mouse J774 cells at 100 uM by XTT assay [AID613474, Type: Literature]
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10
[SID134435028]
Inhibition of LPS-stimulated iNOS mRNA expression in mouse J774 cells by RT-PCR analysis [AID613476, Type: Literature]
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11
[SID134435028]
Inhibition of NF-kB p65 nuclear translocation in LPS-stimulated mouse J774 cells by Western blot analysis [AID613468, Type: Literature]Transcription factor p65 [gi:417926]
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