| 1 | [SID103709193] | Active | Kd | 2.51 | Binding affinity to human adrenergic beta2 receptor [AID426242, Type: Literature] | Beta-2 adrenergic receptor [gi:296439450] |   View X | Row No. | 1 | | Structure | 
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Active | | Kd | 2.51 [uM] | | BioAssay | Binding affinity to human adrenergic beta2 receptor | | AID | 426242 | | BioAssay type | Literature | | Target | Beta-2 adrenergic receptor [gi:296439450] | | PubMed | 19168263 | | Data Table | |
|
| 2 | [SID103709193] | Active | Kd | 2.51 | Binding affinity to human adrenergic beta2 receptor [AID426242, Type: Literature] | Beta-2 adrenergic receptor [gi:296439450] | View X | Row No. | 2 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Active | | Kd | 2.51 [uM] | | BioAssay | Binding affinity to human adrenergic beta2 receptor | | AID | 426242 | | BioAssay type | Literature | | Target | Beta-2 adrenergic receptor [gi:296439450] | | PubMed | 19168263 | | Data Table | |
|
| 3 | [SID103709193] | Active | Kd | 2.51 | Binding affinity to human adrenergic beta2 receptor [AID426242, Type: Literature] | Beta-2 adrenergic receptor [gi:296439450] | View X | Row No. | 3 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Active | | Kd | 2.51 [uM] | | BioAssay | Binding affinity to human adrenergic beta2 receptor | | AID | 426242 | | BioAssay type | Literature | | Target | Beta-2 adrenergic receptor [gi:296439450] | | PubMed | 19168263 | | Data Table | |
|
| 4 | [SID103709193] | Active | Kd | 2.51 | Binding affinity to human adrenergic beta2 receptor [AID426242, Type: Literature] | Beta-2 adrenergic receptor [gi:296439450] | View X | Row No. | 4 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Active | | Kd | 2.51 [uM] | | BioAssay | Binding affinity to human adrenergic beta2 receptor | | AID | 426242 | | BioAssay type | Literature | | Target | Beta-2 adrenergic receptor [gi:296439450] | | PubMed | 19168263 | | Data Table | |
|
| 5 | [SID48414500] | Active | | | DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other] | | View X | Row No. | 5 | | Structure |
| | Substance | | | SID | 48414500 | | CID | 5403 | | Outcome | Active | | BioAssay | DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results | | AID | 1208 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 6 | [SID48414500] | Active | | | DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other] | | View X | Row No. | 6 | | Structure |
| | Substance | | | SID | 48414500 | | CID | 5403 | | Outcome | Active | | BioAssay | DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results | | AID | 1189 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 7 | [SID85209330] | Active | | | Ligands of bioamine (Class A) GPCRs [AID2062, Type: other] | | View X | Row No. | 7 | | Structure |
| | Substance | | | SID | 85209330 | | CID | 5403 | | Outcome | Active | | BioAssay | Ligands of bioamine (Class A) GPCRs | | AID | 2062 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 8 | [SID48416600] | Active | | | DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other] | | View X | Row No. | 8 | | Structure |
| | Substance | | | SID | 48416600 | | CID | 5403 | | Outcome | Active | | BioAssay | DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database | | AID | 1195 | | BioAssay type | other | | Target | | | PubMed | | | Data Table | |
|
| 9 | [SID103709193] | Active | | | Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) [AID40694, Type: Literature] | | View X | Row No. | 9 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Active | | BioAssay | Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | | AID | 40694 | | BioAssay type | Literature | | Target | | | PubMed | 2993621 | | Data Table | |
|
| 10 | [SID103709193] | Active | | | Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA [AID40687, Type: Literature] | Beta-2 adrenergic receptor [gi:2851541] | View X | Row No. | 10 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Active | | BioAssay | Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHA | | AID | 40687 | | BioAssay type | Literature | | Target | Beta-2 adrenergic receptor [gi:2851541] | | PubMed | 2870189 | | Data Table | |
|
| 11 | [SID103709193] | Unspecified | ED50 | 1.04e+06 | Compound was tested for effective dose required for 50% of maximum response in guinea pig trachea [AID76656, Type: Literature] | | View X | Row No. | 11 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | ED50 | 1.04e+06 [uM] | | BioAssay | Compound was tested for effective dose required for 50% of maximum response in guinea pig trachea | | AID | 76656 | | BioAssay type | Literature | | Target | | | PubMed | 6453996 | | Data Table | |
|
| 12 | [SID103709193] | Unspecified | | | Intrinsic activity (n=5) in guinea pig trachea [AID77606, Type: Literature] | | View X | Row No. | 12 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Intrinsic activity (n=5) in guinea pig trachea | | AID | 77606 | | BioAssay type | Literature | | Target | | | PubMed | 6453996 | | Data Table | |
|
| 13 | [SID103709193] | Unspecified | | | Partition coefficient (logD7.4) [AID19419, Type: Literature] | | View X | Row No. | 13 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Partition coefficient (logD7.4) | | AID | 19419 | | BioAssay type | Literature | | Target | | | PubMed | 9544199 | | Data Table | |
|
| 14 | [SID103709193] | Unspecified | | | Human absorption A (%) [AID20050, Type: Literature] | | View X | Row No. | 14 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Human absorption A (%) | | AID | 20050 | | BioAssay type | Literature | | Target | | | PubMed | 9544199 | | Data Table | |
|
| 15 | [SID103709193] | Unspecified | | | Effective permeability measured in human. [AID21264, Type: Literature] | | View X | Row No. | 15 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Effective permeability measured in human. | | AID | 21264 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 16 | [SID103709193] | Unspecified | | | Intrinsic activity in guinea pig trachea [AID77607, Type: Literature] | | View X | Row No. | 16 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Intrinsic activity in guinea pig trachea | | AID | 77607 | | BioAssay type | Literature | | Target | | | PubMed | 6453996 | | Data Table | |
|
| 17 | [SID103709193] | Unspecified | | | Binding to POPC (palmitoyl-oleolyl-phosphatidyl-choline) liposomes using biosensor system [AID156089, Type: Literature] | | View X | Row No. | 17 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Binding to POPC (palmitoyl-oleolyl-phosphatidyl-choline) liposomes using biosensor system | | AID | 156089 | | BioAssay type | Literature | | Target | | | PubMed | 10841786 | | Data Table | |
|
| 18 | [SID103709193] | Unspecified | | | Binding to POPC/GMI liposomes using biosensor system [AID156203, Type: Literature] | | View X | Row No. | 18 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Binding to POPC/GMI liposomes using biosensor system | | AID | 156203 | | BioAssay type | Literature | | Target | | | PubMed | 10841786 | | Data Table | |
|
| 19 | [SID103709193] | Unspecified | | | Change in Gibb's free energy at Low affinity beta-2-adrenoreceptor in the membranes of bovine skeletal muscle preparation [AID218845, Type: Literature] | | View X | Row No. | 19 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Change in Gibb's free energy at Low affinity beta-2-adrenoreceptor in the membranes of bovine skeletal muscle preparation | | AID | 218845 | | BioAssay type | Literature | | Target | | | PubMed | 2836587 | | Data Table | |
|
| 20 | [SID103709193] | Unspecified | | | Change in Gibb's free energy at High affinity beta2- adrenoceptor in Chang living cells. [AID218847, Type: Literature] | | View X | Row No. | 20 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Change in Gibb's free energy at High affinity beta2- adrenoceptor in Chang living cells. | | AID | 218847 | | BioAssay type | Literature | | Target | | | PubMed | 2836587 | | Data Table | |
|
| 21 | [SID103709193] | Unspecified | | | Change in Gibb's free energy at Low affinity beta-2-adrenoreceptor in the Chang living cells [AID218848, Type: Literature] | | View X | Row No. | 21 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Change in Gibb's free energy at Low affinity beta-2-adrenoreceptor in the Chang living cells | | AID | 218848 | | BioAssay type | Literature | | Target | | | PubMed | 2836587 | | Data Table | |
|
| 22 | [SID103709193] | Unspecified | | | Fraction absorbed in human intestine after oral administration compound was measured [AID236268, Type: Literature] | | View X | Row No. | 22 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Fraction absorbed in human intestine after oral administration compound was measured | | AID | 236268 | | BioAssay type | Literature | | Target | | | PubMed | 15658873 | | Data Table | |
|
| 23 | [SID103709193] | Unspecified | | | Permeability Coefficient in 2/4/A1 cell model [AID236912, Type: Literature] | | View X | Row No. | 23 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Permeability Coefficient in 2/4/A1 cell model | | AID | 236912 | | BioAssay type | Literature | | Target | | | PubMed | 15658873 | | Data Table | |
|
| 24 | [SID103709193] | Unspecified | | | Permeability Coefficient in Caco-2 cell culture model [AID236913, Type: Literature] | | View X | Row No. | 24 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Permeability Coefficient in Caco-2 cell culture model | | AID | 236913 | | BioAssay type | Literature | | Target | | | PubMed | 15658873 | | Data Table | |
|
| 25 | [SID103709193] | Unspecified | | | Permeability Coefficient in hexadecane membranes model [AID236914, Type: Literature] | | View X | Row No. | 25 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Permeability Coefficient in hexadecane membranes model | | AID | 236914 | | BioAssay type | Literature | | Target | | | PubMed | 15658873 | | Data Table | |
|
| 26 | [SID103709193] | Unspecified | | | Percentage of mass balance in hexadecane membranes model [AID236916, Type: Literature] | | View X | Row No. | 26 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Percentage of mass balance in hexadecane membranes model | | AID | 236916 | | BioAssay type | Literature | | Target | | | PubMed | 15658873 | | Data Table | |
|
| 27 | [SID103709193] | Unspecified | | | Clearance in human [AID310711, Type: Literature] | | View X | Row No. | 27 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Clearance in human | | AID | 310711 | | BioAssay type | Literature | | Target | | | PubMed | 17976986 | | Data Table | |
|
| 28 | [SID103709193] | Unspecified | | | Fraction unbound in human plasma [AID444050, Type: Literature] | | View X | Row No. | 28 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Fraction unbound in human plasma | | AID | 444050 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 29 | [SID103709193] | Unspecified | | | Total clearance in human [AID444051, Type: Literature] | | View X | Row No. | 29 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Total clearance in human | | AID | 444051 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 30 | [SID103709193] | Unspecified | | | Hepatic clearance in human [AID444052, Type: Literature] | | View X | Row No. | 30 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Hepatic clearance in human | | AID | 444052 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 31 | [SID103709193] | Unspecified | | | Renal clearance in human [AID444053, Type: Literature] | | View X | Row No. | 31 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Renal clearance in human | | AID | 444053 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 32 | [SID103709193] | Unspecified | | | Oral bioavailability in human [AID444054, Type: Literature] | | View X | Row No. | 32 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Oral bioavailability in human | | AID | 444054 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 33 | [SID103709193] | Unspecified | | | Fraction absorbed in human [AID444055, Type: Literature] | | View X | Row No. | 33 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Fraction absorbed in human | | AID | 444055 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 34 | [SID103709193] | Unspecified | | | Fraction escaping gut-wall elimination in human [AID444056, Type: Literature] | | View X | Row No. | 34 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Fraction escaping gut-wall elimination in human | | AID | 444056 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 35 | [SID103709193] | Unspecified | | | Fraction escaping hepatic elimination in human [AID444057, Type: Literature] | | View X | Row No. | 35 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Fraction escaping hepatic elimination in human | | AID | 444057 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 36 | [SID103709193] | Unspecified | | | Volume of distribution at steady state in human [AID444058, Type: Literature] | | View X | Row No. | 36 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Volume of distribution at steady state in human | | AID | 444058 | | BioAssay type | Literature | | Target | | | PubMed | 20070106 | | Data Table | |
|
| 37 | [SID103709193] | Unspecified | | | Permeability at pH 6.5 by PAMPA method [AID445445, Type: Literature] | | View X | Row No. | 37 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Permeability at pH 6.5 by PAMPA method | | AID | 445445 | | BioAssay type | Literature | | Target | | | PubMed | 19947605 | | Data Table | |
|
| 38 | [SID103709193] | Unspecified | | | Oral bioavailability in human [AID445446, Type: Literature] | | View X | Row No. | 38 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Oral bioavailability in human | | AID | 445446 | | BioAssay type | Literature | | Target | | | PubMed | 19947605 | | Data Table | |
|
| 39 | [SID103709193] | Unspecified | | | Unbound fraction (plasma) [AID7783, Type: Literature] | | View X | Row No. | 39 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Unbound fraction (plasma) | | AID | 7783 | | BioAssay type | Literature | | Target | | | PubMed | 14971904 | | Data Table | |
|
| 40 | [SID103709193] | Unspecified | | | Observed volume of distribution [AID8002, Type: Literature] | | View X | Row No. | 40 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Observed volume of distribution | | AID | 8002 | | BioAssay type | Literature | | Target | | | PubMed | 14971904 | | Data Table | |
|
| 41 | [SID103709193] | Unspecified | | | Calculated partition coefficient (clogP) [AID15711, Type: Literature] | | View X | Row No. | 41 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Calculated partition coefficient (clogP) | | AID | 15711 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 42 | [SID103709193] | Unspecified | | | Estimation of fraction absorbed (Fa) in the human intestine using biosensor technology. [AID18849, Type: Literature] | | View X | Row No. | 42 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Estimation of fraction absorbed (Fa) in the human intestine using biosensor technology. | | AID | 18849 | | BioAssay type | Literature | | Target | | | PubMed | 10841786 | | Data Table | |
|
| 43 | [SID103709193] | Unspecified | | | GOF value represents multisets of log P data [AID18861, Type: Literature] | | View X | Row No. | 43 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | GOF value represents multisets of log P data | | AID | 18861 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 44 | [SID103709193] | Unspecified | | | Delta logD (logD6.5 - logD7.4) [AID22293, Type: Literature] | | View X | Row No. | 44 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Delta logD (logD6.5 - logD7.4) | | AID | 22293 | | BioAssay type | Literature | | Target | | | PubMed | 10891117 | | Data Table | |
|
| 45 | [SID103709193] | Unspecified | | | log(1/ISA) value of the compound [AID24177, Type: Literature] | | View X | Row No. | 45 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | log(1/ISA) value of the compound | | AID | 24177 | | BioAssay type | Literature | | Target | | | PubMed | 2870189 | | Data Table | |
|
| 46 | [SID103709193] | Unspecified | | | Distribution coefficient in octanol/water at pH 5.5 [AID24202, Type: Literature] | | View X | Row No. | 46 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Distribution coefficient in octanol/water at pH 5.5 | | AID | 24202 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 47 | [SID103709193] | Unspecified | | | Distribution coefficient in octanol/water at pH 6.5 [AID24203, Type: Literature] | | View X | Row No. | 47 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Distribution coefficient in octanol/water at pH 6.5 | | AID | 24203 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 48 | [SID103709193] | Unspecified | | | Distribution coefficient in octanol/water at pH 7.4 [AID24204, Type: Literature] | | View X | Row No. | 48 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Distribution coefficient in octanol/water at pH 7.4 | | AID | 24204 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 49 | [SID103709193] | Unspecified | | | Partition coefficient (logP) [AID24420, Type: Literature] | | View X | Row No. | 49 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Partition coefficient (logP) | | AID | 24420 | | BioAssay type | Literature | | Target | | | PubMed | 9836611 | | Data Table | |
|
| 50 | [SID103709193] | Unspecified | | | Calculated partition coefficient (clogP) [AID24440, Type: Literature] | | View X | Row No. | 50 | | Structure |
| | Substance | | | SID | 103709193 | | CID | 5403 | | Outcome | Unspecified | | BioAssay | Calculated partition coefficient (clogP) | | AID | 24440 | | BioAssay type | Literature | | Target | | | PubMed | 2870189 | | Data Table | |
|
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
