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Dihydromorphine (CID 5359421) - Compound BioActivity Data
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BioActivity Outcomes:
Active(8)
 
 
Inactive(89)
 
 
Inconclusive(4)
 
 
Unspecified(15)
 
 
Top Targets:
7TM GPCR Srx(11)
 
 
 
NR LBD PPAR(8)
 
 
 
NR LBD AR(7)
 
 
NR LBD ER(7)
 
 
7TM GPCR Srsx(6)
 
 
 
 
BioAssay Types:
Confirmatory(67)
 
 
 
Summary(24)
 
 
 
Literature(23)
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(85)
 
 
 
Kd(8)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 104    Data Row: 116   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103556978]
Kd 0.0002Evaluated for Opioid receptor mu 1 affinity against the receptor site model site 1(mu1) [AID151463, Type: Literature]Mu-type opioid receptor [gi:464314]
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2
[SID103556978]
Kd 0.01Opioid receptor mu 2 affinity against the receptor site model site 2(mu2) [AID152211, Type: Literature]Mu-type opioid receptor [gi:464314]
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3
[SID103556978]
Kd 0.1Affinity against the Opioid receptor delta 1 [AID149533, Type: Literature]Delta-type opioid receptor [gi:464311]
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4
[SID103556978]
Kd 0.2Compound was evaluated for opioid receptor affinity against the receptor site model site 5 [AID149052, Type: Literature]Mu-type opioid receptor [gi:464314]
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5
[SID103556978]
Kd 0.2Compound was evaluated for opioid receptor affinity against the receptor site model site 5 [AID149052, Type: Literature]Delta-type opioid receptor [gi:464311]
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6
[SID103556978]
Kd 0.2Compound was evaluated for opioid receptor affinity against the receptor site model site 5 [AID149052, Type: Literature]Sigma non-opioid intracellular receptor 1 [gi:81882051]
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7
[SID103556978]
Kd 0.2Compound was evaluated for opioid receptor affinity against the receptor site model site 5 [AID149052, Type: Literature]Kappa-type opioid receptor [gi:464313]
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8
[SID103556978]
Kd 0.83Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) [AID148456, Type: Literature]
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9
[SID103556978]
Permeability coefficient in human skin [AID311367, Type: Literature]
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10
[SID103556978]
Antinociceptive activity in sc dosed mouse [AID647793, Type: Literature]
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11
[SID103556978]
pKa (acid-base dissociation constant) as determined by Liao ref: J Chem Info Model 2009 [AID781325, Type: Literature]
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12
[SID103556978]
The ratio between [3H]naloxone binding in the presence and absence of 100 mM NaCl [AID233531, Type: Literature]Sigma non-opioid intracellular receptor 1 [gi:81882051]
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13
[SID103556978]
Inhibition of [3H]naloxone receptor binding to opioid receptor in the absence of 100 mM NaCl [AID149048, Type: Literature]Sigma non-opioid intracellular receptor 1 [gi:81882051]
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14
[SID103556978]
Inhibition of [3H]naloxone receptor binding to opioid receptor in the presence of 100 mM NaCl [AID149050, Type: Literature]Sigma non-opioid intracellular receptor 1 [gi:81882051]
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15
[SID103556978]
The ratio between [3H]naloxone binding in the presence and absence of 100 mM NaCl [AID233531, Type: Literature]Delta-type opioid receptor [gi:464311]
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16
[SID103556978]
The ratio between [3H]naloxone binding in the presence and absence of 100 mM NaCl [AID233531, Type: Literature]Kappa-type opioid receptor [gi:464313]
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17
[SID103556978]
Inhibition of [3H]naloxone receptor binding to opioid receptor in the presence of 100 mM NaCl [AID149050, Type: Literature]Kappa-type opioid receptor [gi:464313]
View
18
[SID103556978]
Inhibition of [3H]naloxone receptor binding to opioid receptor in the absence of 100 mM NaCl [AID149048, Type: Literature]Kappa-type opioid receptor [gi:464313]
View
19
[SID103556978]
Inhibition of [3H]naloxone receptor binding to opioid receptor in the absence of 100 mM NaCl [AID149048, Type: Literature]Mu-type opioid receptor [gi:464314]
View
20
[SID103556978]
The ratio between [3H]naloxone binding in the presence and absence of 100 mM NaCl [AID233531, Type: Literature]Mu-type opioid receptor [gi:464314]
View