Bookmark and Share
Dacarbazine (CID 5351166) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(73)
 
 
Inactive(918)
 
 
Inconclusive(70)
 
 
Unspecified(212)
 
 
Top Targets:
7TM GPCR Srx(36)
 
 
 
7TM GPCR Srsx(30)
 
 
 
p450(25)
 
 
 
 
HSD10-like SD..(8)
 
 
ANK(8)
 
 
BioAssay Types:
Confirmatory(631)
 
 
 
 
 
Screening(323)
 
 
 
Literature(157)
 
 
 
 
 
BioActivity Types:
Potency(359)
 
 
 
 
 
IC50(145)
 
 
 
 
 
AC50(5)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1022    Data Row: 1273   Total Pages: 64   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103168962]
IC50 0.556DRUGMATRIX: Protease, Matrix Metalloprotease-9 (MMP-9) enzyme inhibition (substrate: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) [AID625178, Type: confirmatory]Matrix metalloproteinase-9 [gi:269849668]
View
2
[SID57260110]
IC50 4.86High Throughput Screening Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in 7H9 Media [AID449762, Type: confirmatory]
View
3
[SID57260110]
IC50 5.04A High Throughput Confirmatory Assay used to Identify Novel Compounds that Inhibit Mycobacterium Tuberculosis in the absence of Glycerol [AID449764, Type: confirmatory]
View
4
[SID57260110]
AC50_uM 5.34HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity [AID687027, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
View
5
[SID103168962]
IC50 7.67Cytotoxicity against human GC3/C1 cells after 6 days by MTT assay [AID550849, Type: Literature]
View
6
[SID103168962]
IC50 11.83Cytotoxicity against human UACC62 cells after 6 days by MTT assay [AID550848, Type: Literature]
View
7
[SID103168962]
IC50 14In vitro cytotoxicity against human lymphoblastoid cell (GM892 A) [AID73186, Type: Literature]
View
8
[SID103168962]
IC50 17.67Cytotoxicity against human OVCAR3 cells after 6 days by MTT assay [AID550850, Type: Literature]
View
9
[SID17389952]
Potency 74.978qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
View
10
[SID103168962]
Inhibition of human CYP1A2 assessed as ratio of IC50 in absence of NADPH to IC50 for presence of NADPH using ethoxyresorufin as substrate after 30 mins [AID678712, Type: Literature]Cytochrome P450 1A2 [gi:117144]
View
11
[SID57260110]
Counterscreen for inhibitors of AddAB: absorbance-based bacterial cell-based high throughput screening assay to identify inhibitors of bacterial viability [AID449728, Type: screening]
View
12
[SID48413510]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary SingleCellCall Results [AID1189, Type: other]
View
13
[SID48413510]
DSSTox (CPDBAS) Carcinogenic Potency Database Salmonella Mutagenicity [AID1194, Type: other]
View
14
[SID48413510]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Mouse Bioassay Results [AID1199, Type: other]
View
15
[SID48413510]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary MultiCellCall Results [AID1205, Type: other]
View
16
[SID48413510]
DSSTox (CPDBAS) Carcinogenic Potency Database Summary Rat Bioassay Results [AID1208, Type: other]
View
17
[SID48415838]
DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
View
18
[SID57260110]
Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput confirmation assay for inhibitors of bacterial viability [AID488956, Type: screening]
View
19
[SID103168962]
DNA inhibitor [AID742711, Type: other]
View
20
[SID99125]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Ependymoblastoma (intracerebral) in B6C3F1 mice [AID226, Type: other]
View