CHEMBL2070962 (CID 53488284) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(1)
 
 
Top Targets:
KCNQ channel(1)
 
 
BioAssay Types:
Literature(2)
 
 
 
Confirmatory(1)
 
 
BioActivity Types:
EC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 3    Data Row: 3   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID126700207]
EC50 0.77753SAR analysis for compounds that activate KCNQ1 potassium channels in the KCNQ1 expressing cells on automated patch clamp 2 [AID602121, Type: confirmatory]KCNQ1 gene product [Homo sapiens] [gi:32479527]
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2
[SID160670058]
EC50 0.78Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay [AID678686, Type: Literature]
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3
[SID160670058]
 Activation of Kv7.1 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay relative to control [AID678687, Type: Literature]
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