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CHEMBL2170942 (CID 53481937) - Compound BioActivity Data
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BioActivity Outcomes:
Inactive(4)
 
 
Unspecified(2)
 
 
Top Targets:
G6PD N(3)
 
 
G6PD C(2)
 
 
 
BioAssay Types:
Confirmatory(4)
 
 
Literature(2)
 
 
BioActivity Types:
IC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 6    Data Row: 6   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID163327866]
IC50 80Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assay [AID701903, Type: Literature]Glucose-6-phosphate dehydrogenase [gi:74895034]
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2
[SID163327866]
IC50 80Inhibition of human glucose-6-phosphate dehydrogenase after 90 mins by resazurin/diaphorasecoupled assay [AID701899, Type: Literature]Glucose-6-phosphate 1-dehydrogenase [gi:116242483]
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3
[SID126531633]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay - Set 3 [AID602130, Type: confirmatory]glucose-6-phosphate 1-dehydrogenase isoform b [Homo sapiens] [gi:108773793]
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4
[SID126531633]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay - Set 3 [AID602131, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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5
[SID126531633]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal assay utilizing the direct end-point detection of NADPH - Set 2 [AID602132, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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6
[SID126531633]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH - Set 2 [AID602133, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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