CHEMBL1818231 (CID 53465639) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(3)
 
 
Top Targets:
7TM GPCR Srx(2)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
Ki(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134455250]
Ki 0.053Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613641, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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2
[SID134455250]
Ki 0.053Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613641, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
3
[SID134455250]
Ki 0.053Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613641, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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4
[SID134455250]
Ki 0.053Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613641, Type: Literature]Kappa-type opioid receptor [gi:116242691]
View
5
[SID134455250]
Ki 0.735Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613642, Type: Literature]Mu-type opioid receptor [gi:2851402]
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6
[SID134455250]
Ki 0.735Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613642, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
7
[SID134455250]
Ki 0.735Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613642, Type: Literature]Mu-type opioid receptor [gi:2851402]
View
8
[SID134455250]
Ki 0.735Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting [AID613642, Type: Literature]Mu-type opioid receptor [gi:2851402]
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9
[SID134455250]
 Clearance in human liver microsomes [AID613645, Type: Literature]
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10
[SID134455250]
 Selectivity, ratio of Ki for human mu opioid receptor to Ki for human kappa opioid receptor [AID613646, Type: Literature]
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11
[SID134455250]
 Efflux ratio of permeability from basolateral to apical side over apical to basolateral side in MDCK cells expressing human MDR1 [AID613644, Type: Literature]
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