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F0921-4352 (CID 5344820) - Compound BioActivity Data
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BioActivity Outcomes:
Active(74)
 
 
Inactive(507)
 
 
Inconclusive(19)
 
 
Unspecified(5)
 
 
Top Targets:
7TM GPCR Srx(21)
 
 
7TM GPCR Srsx(15)
 
 
Firefly Luc l..(11)
 
 
Peptidase C48(8)
 
 
 
PP1c bdg(6)
 
 
 
 
BioAssay Types:
Screening(388)
 
 
 
 
Confirmatory(201)
 
 
 
 
 
Literature(11)
 
 
BioActivity Types:
Potency(131)
 
 
 
 
 
IC50(38)
 
 
 
 
AC50(15)
 
 
 
 
EC50(6)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 547    Data Row: 605   Total Pages: 31   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49728465]
Potency 0.0073FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM ATP [AID602364, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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2
[SID49728465]
Potency 0.0092FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate and 500microM CoASH [AID602358, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID49728465]
Potency 0.0239qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID49728465]
Potency 0.0283FLuc inhibitory activity for the follow-up compounds in a biochemical assay with a commercial detection reagent - BriteliteTM Plus (PerkinElmer) [AID602474, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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5
[SID49728465]
Potency 0.0291FLuc inhibitory activity for the follow-up compounds in a biochemical assay with Km concentrations of substrate [AID602357, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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6
[SID115950064]
AC50_uM 0.06Assay of luciferase inhibitors in dose Measured in Biochemical System Using Plate Reader - 2078-05_Inhibitor_Dose_DryPowder_Activity [AID588451, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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7
[SID49728465]
Potency 0.0619FLuc inhibitory activity for the follow-up compounds in a biochemical assay with an in-house formulation of detection reagent [AID602475, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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8
[SID49728465]
Potency 0.1834FLuc inhibitory activity for the follow-up compounds in a biochemical assay with 1mM D-luciferin [AID602365, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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9
[SID49728465]
Potency 0.2005FLuc inhibitory activity for the follow-up compounds in a cell-based assay to assess the activity of miR-21 [AID602477, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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10
[SID115950064]
AC50_uM 0.244Amyloid Precursor 5' UTR neuroblastoma cell reporter line Measured in Cell-Based System Using Plate Reader - 2078-04_Inhibitor_Dose_DryPowder_Activity [AID540343, Type: confirmatory]
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11
[SID49728465]
Potency 0.5012qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
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12
[SID115950064]
AC50_uM 0.731Inhibitors of Prion Protein 5' UTR mRNA Measured in Cell-Based System Using Plate Reader - 2078-01_Inhibitor_Dose_DryPowder_Activity [AID504932, Type: confirmatory]
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13
[SID49728465]
EC50 0.994Luminescence Biochemical Dose Response HTS to Identify Inhibitors of Luciferase [AID1891, Type: confirmatory]
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14
[SID49728465]
Potency 1.122qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
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15
[SID49728465]
EC50 1.602Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Platelet Dense Granule Release [AID1889, Type: confirmatory]
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16
[SID49728465]
Potency 2.2492FLuc inhibitory activity for the follow-up compounds in a cell-based translational read-through assay (72 hour incubation) [AID602478, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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17
[SID49728465]
Potency 2.5119qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode) [AID624417, Type: confirmatory]glp-1 receptor [Homo sapiens] [gi:1724069]
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18
[SID49728465]
Potency 3.5648FLuc inhibitory activity for the follow-up compounds in a cell-based translational read-through assay [AID602476, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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19
[SID49728465]
Potency 5.6234qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]pyruvate kinase PKM isoform a [Homo sapiens] [gi:33286418]
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20
[SID49728465]
Potency 6.5064qHTS for inhibitors of Phosphogylcerate Kinase: Hit Validation Screen [AID686980, Type: confirmatory]phosphoglycerate kinase [Trypanosoma brucei] [gi:115503961]
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