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AGN-PC-09SAJ3 (CID 53384783) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Inactive(2)
 
 
Top Targets:
G6PD N(3)
 
 
 
G6PD C(1)
 
 
BioAssay Types:
Confirmatory(4)
 
 
 
BioActivity Types:
IC50(4)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 4    Data Row: 4   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125311527]
IC50_Mean 18.3SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal kinetic assay utilizing the direct detection of NADPH - Set 2 [AID602133, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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2
[SID125311527]
IC50_Mean 25.4SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase in an orthogonal assay utilizing the direct end-point detection of NADPH - Set 2 [AID602132, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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3
[SID125311527]
IC50_Mean 20.4SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay - Set 3 [AID602131, Type: confirmatory]glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase [Plasmodium berghei] [gi:12381848]
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4
[SID125311527]
IC50_Mean 80SAR analysis of small molecule inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase using a Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay - Set 3 [AID602130, Type: confirmatory]glucose-6-phosphate 1-dehydrogenase isoform b [Homo sapiens] [gi:108773793]
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