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AGN-PC-09S9KJ (CID 53383425) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(111)
 
 
Inconclusive(3)
 
 
Top Targets:
7TM GPCR Srsx(5)
 
 
7TM GPCR Srx(4)
 
 
RasGEF(4)
 
 
NR DBD CAR(3)
 
 
ANK(2)
 
 
BioAssay Types:
Screening(96)
 
 
 
Confirmatory(22)
 
 
 
 
BioActivity Types:
Potency(22)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 112    Data Row: 118   Total Pages: 6   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125306098]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID125306098]
HIV entry: Env-mediated Cell Fusion Measured in Cell-Based System Using Plate Reader - 7013-01_Inhibitor_SinglePoint_HTS_Activity [AID651610, Type: screening]
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3
[SID125306098]
DENV2 CPE-Based HTS Measured in Cell-Based and Microorganism Combination System Using Plate Reader - 2149-01_Other_SinglePoint_HTS_Activity [AID651640, Type: screening]
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4
[SID125306098]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) [AID651572, Type: screening]ADP-ribosylation factor GTPase-activating protein 1 [Rattus norvegicus] [gi:21489979]
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5
[SID125306098]
Potency 50.1187qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2): primary screen [AID720708, Type: confirmatory]Rap guanine nucleotide exchange factor 4 [gi:32171491]
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6
[SID125306098]
Potency qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2): primary screen [AID720711, Type: confirmatory]Rap guanine nucleotide exchange factor 4 [gi:32171491]
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7
[SID125306098]
Primary biochemical fluorescence polarization-based high throughput screening assay to identify inhibitors of protein arginine methyltransferase 1 (PRMT1) [AID652257, Type: screening]PRMT1 protein, partial [Homo sapiens] [gi:32425330]
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8
[SID125306098]
uHTS identification of small molecule inhibitors of Csn-mediated Deneddylation of Cullin-Ring Ligases, vis a fluorescence polarization assay [AID651999, Type: screening]COP9 signalosome complex subunit 5 [Homo sapiens] [gi:38027923]
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9
[SID125306098]
uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]endothelial PAS domain-containing protein 1 [Homo sapiens] [gi:40254439]
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10
[SID125306098]
S100A4: HTS Measured in Biochemical System Using Plate Reader - 7045-01_Inhibitor_SinglePoint_HTS_Activity [AID652163, Type: screening]S100A4, partial [Homo sapiens] [gi:47496637]
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11
[SID125306098]
uHTS identification of small molecule activators of alpha dystroglycan glycosylation [AID624168, Type: screening]LARGE [Homo sapiens] [gi:47678551]
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12
[SID125306098]
TRFRET-based biochemical primary high throughput screening assay to identify inhibitors of 5-meCpG-binding domain protein 2 (MBD2)-DBD binding to methylated oligonucleotide [AID686964, Type: screening]Methyl-CpG binding domain protein 2 [Homo sapiens] [gi:21595776]
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13
[SID125306098]
Potency qHTS for Inhibitors of AMA1-RON; Towards Development of Antimalarial Drug Lead: Primary Screen [AID720542, Type: confirmatory]apical membrane antigen 1, AMA1 [Plasmodium falciparum 3D7] [gi:23496270]
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14
[SID125306098]
Epi Absorbance-based biochemical primary high throughput screening assay to identify inhibitors of human tyrosyl-DNA phosphodiesterase 2 (TDP2) [AID720702, Type: screening]tyrosyl-DNA phosphodiesterase 2 [Homo sapiens] [gi:23510348]
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15
[SID125306098]
uHTS identification of SKN-1 Inhibitors in a fluoresence assay [AID624304, Type: screening]Protein SKN-1, isoform b [Caenorhabditis elegans] [gi:25148072]
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16
[SID125306098]
Luminescence-based cell-based primary high throughput screening assay to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) [AID624169, Type: screening]5-hydroxytryptamine receptor 2A [Mus musculus] [gi:27753985]
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17
[SID125306098]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn7) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] [AID720508, Type: screening]Chain E, Fragment Double-D From Human Fibrin [gi:28373962]
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18
[SID125306098]
Fluorescence polarization-based biochemical primary high throughput screening assay to identify inhibitors that disrupt the binding of a cyclic peptide (Tn6) to the fibrin proteolytic product D-Dimer and fragment E complex [DD(E )] [AID720509, Type: screening]Chain E, Fragment Double-D From Human Fibrin [gi:28373962]
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19
[SID125306098]
Potency qHTS Assay for Inhibitors of the HIV-1 protein Vpr [AID651644, Type: confirmatory]Vpr [Human immunodeficiency virus 1] [gi:28872817]
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20
[SID125306098]
Luminescence-based biochemical primary high throughput screening assay to identify inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) [AID602281, Type: screening]1-acylglycerol-3-phosphate O-acyltransferase ABHD5 [Homo sapiens] [gi:31542303]
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