MLS003678875 (CID 53382823) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(3)
 
 
Inactive(74)
 
 
Inconclusive(3)
 
 
Top Targets:
NR DBD CAR(3)
 
 
7TM GPCR Srsx(2)
 
 
7TM GPCR Srx(2)
 
 
OTU(1)
 
 
P5 C(1)
 
 
BioAssay Types:
Screening(67)
 
 
 
Confirmatory(13)
 
 
 
 
BioActivity Types:
Potency(13)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 80    Data Row: 80   Total Pages: 2   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125305467]
Potency 10.3225qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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2
[SID125305467]
Potency 10.3225qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID125305467]
Potency 10.3225qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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4
[SID125305467]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID125305467]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID125305467]
Potency 12.9953qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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7
[SID125305467]
 Luminescence-based cell-based primary high throughput screening assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 [AID652010, Type: screening]NR0B1 gene product [Homo sapiens] [gi:5016090]
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8
[SID125305467]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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9
[SID125305467]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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10
[SID125305467]
 HTS Assay for Inhibitors of Akt Phophorylation: Primary Screen [AID651550, Type: screening]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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11
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
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12
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
13
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
14
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624126, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
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15
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624126, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
16
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624126, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
17
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624127, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
18
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624127, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
19
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624127, Type: screening]CHRM4 gene product [Homo sapiens] [gi:52426748]
View
20
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624037, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
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21
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624037, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
22
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624037, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
23
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify agonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624037, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
24
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624038, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
25
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624038, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
26
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624038, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
27
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify positive allosteric modulators (PAMs) of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624038, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
28
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
29
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
30
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
31
[SID125305467]
 Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 5 (CHRM5) [AID624040, Type: screening]CHRM5 gene product [Homo sapiens] [gi:7108336]
View
32
[SID125305467]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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33
[SID125305467]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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34
[SID125305467]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
35
[SID125305467]
 qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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36
[SID125305467]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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37
[SID125305467]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
38
[SID125305467]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
39
[SID125305467]
 qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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40
[SID125305467]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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41
[SID125305467]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
42
[SID125305467]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
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43
[SID125305467]
 qHTS of D3 Dopamine Receptor Antagonist: qHTS [AID652054, Type: screening]DRD3 gene product [Homo sapiens] [gi:89191863]
View
44
[SID125305467]
 uHTS identification of small molecule antagonists of the EBI2 receptor via a luminescent beta-arrestin assay [AID651636, Type: screening]GPR183 gene product [Homo sapiens] [gi:4826706]
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45
[SID125305467]
 uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]EPAS1 gene product [Homo sapiens] [gi:40254439]
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46
[SID125305467]
 uHTS identification of HIF-2a Inhibitors in a luminesence assay [AID624352, Type: screening]EPAS1 gene product [Homo sapiens] [gi:40254439]
View
47
[SID125305467]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
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48
[SID125305467]
 Luminescence-based cell-based primary high throughput screening assay to identify inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2) [AID602396, Type: screening]NR5A2 gene product [Homo sapiens] [gi:4504343]
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49
[SID125305467]
 Inhibition of the MLL-AF4-AF9 Interaction in Pediatric Leukemia Measured in Biochemical System Using Plate Reader - 2160-01_Inhibitor_SinglePoint_HTS_Activity [AID651704, Type: screening]MLLT3 gene product [Homo sapiens] [gi:156104889]
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50
[SID125305467]
 uHTS identification of inhibitors of MT1-MMP activation in a fluoresence assay [AID651647, Type: screening]MMP14 gene product [Homo sapiens] [gi:4826834]
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