MLS003874819 (CID 53364507) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Probe(1)
 
 
Active(17)
 
 
Inactive(89)
 
 
Unspecified(4)
 
 
Top Targets:
Peptidase S9(26)
 
 
 
 
Esterase lipa..(8)
 
 
 
BAAT C(6)
 
 
Esterase 713..(5)
 
 
PRK11460(5)
 
 
BioAssay Types:
Screening(11)
 
 
 
Confirmatory(5)
 
 
 
Summary(5)
 
 
 
BioActivity Types:
IC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 23    Data Row: 111   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125269079]
 Summary of probe development efforts to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463092, Type: summary]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
2
[SID125269079]
 Summary of probe development efforts to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463092, Type: summary]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
3
[SID125269079]
IC50 0.006Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based dose response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of human pPAFAH [AID588766, Type: confirmatory]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
4
[SID125269079]
IC50 0.006Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based dose response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of human pPAFAH [AID588766, Type: confirmatory]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
5
[SID125269079]
IC50 0.031Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based dose-response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) assay for SAR compounds [AID588770, Type: confirmatory]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
6
[SID125269079]
IC50 0.031Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based dose-response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) assay for SAR compounds [AID588770, Type: confirmatory]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
7
[SID125269079]
IC50 0.031Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based dose-response biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) assay for SAR compounds [AID588770, Type: confirmatory]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
8
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition and selectivity of SAR compounds in a complex proteome [AID588774, Type: other]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
9
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition and selectivity of SAR compounds in a complex proteome [AID588774, Type: other]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
10
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition and selectivity of SAR compounds in a complex proteome [AID588774, Type: other]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
11
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition and selectivity of SAR compounds in a complex proteome [AID588774_1, Type: other]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
12
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition and selectivity of SAR compounds in a complex proteome [AID588774_1, Type: other]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
13
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of plasma platelet activating factor acetylhydrolase (pPAFAH): fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition and selectivity of SAR compounds in a complex proteome [AID588774_1, Type: other]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View
14
[SID143472339]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]NR2F2 gene product [Homo sapiens] [gi:14149746]
View
15
[SID143472339]
 Luminescence-based cell-based primary high throughput screening assay to identify inhibitors of COUP-TFII (NR2F2) [AID686940, Type: screening]NR2F2 gene product [Homo sapiens] [gi:14149746]
View
16
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical assay to determine binding mode of test compounds [AID588788, Type: other]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
17
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical assay to determine binding mode of test compounds [AID588788, Type: other]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
18
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785_39, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
19
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785_39, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
20
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785_39, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
21
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787_15, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
22
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787_15, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
23
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787_15, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
24
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH and selectivity analysis in vivo [AID588823, Type: other]Es1 protein [Mus musculus] [gi:22135640]
View
25
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH and selectivity analysis in vivo [AID588823, Type: other]Es1 protein [Mus musculus] [gi:22135640]
View
26
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH and selectivity analysis in vivo [AID588823_1, Type: other]Es1 protein [Mus musculus] [gi:22135640]
View
27
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH and selectivity analysis in vivo [AID588823_1, Type: other]Es1 protein [Mus musculus] [gi:22135640]
View
28
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH and selectivity analysis in vivo [AID588823_2, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
29
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH and selectivity analysis in vivo [AID588823_2, Type: other]Ces1c gene product [Mus musculus] [gi:247269929]
View
30
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
31
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
32
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
33
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785_1, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
34
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785_1, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
35
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain membrane proteome [AID588785_1, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
36
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
37
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
38
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
39
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787_1, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
40
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787_1, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
41
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: LC-MS/MS-based biochemical ABPP-MudPIT assay to determine selectivity of test compounds in the mouse brain soluble proteome [AID588787_1, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
42
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH in vivo [AID588789, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
43
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH in vivo [AID588789, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
44
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH in vivo [AID588789, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
45
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH in situ [AID588817, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
46
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH in situ [AID588817, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
47
[SID125269079]
 Late stage assay provider results from the probe development effort to identify inhibitors of pPAFAH: fluorescence-based biochemical gel-based competitive Activity-Based Protein Profiling (ABPP) inhibition of pPAFAH in situ [AID588817, Type: other]platelet-activating factor acetylhydrolase precursor [Mus musculus] [gi:31980752]
View
48
[SID125269079]
 Summary of probe development efforts to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463092_1, Type: summary]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
49
[SID125269079]
 Summary of probe development efforts to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463092_1, Type: summary]PLA2G7 gene product [Homo sapiens] [gi:270133071]
View
50
[SID125269079]
 Summary of probe development efforts to identify inhibitors of the plasma platelet activating factor acetylhydrolase (pPAFAH) [AID463092_2, Type: summary]Phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) [Mus musculus] [gi:14715116]
View