BRD-A78834069-001-01-2 (CID 53347989) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(6)
 
 
Inactive(6)
 
 
Top Targets:
CD36(10)
 
 
 
BioAssay Types:
Confirmatory(12)
 
 
 
BioActivity Types:
AC50(11)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 12    Data Row: 12   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125081990]
AC50 0.00319HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set6 [AID588828, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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2
[SID125081990]
AC50 0.0154HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID588392, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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3
[SID125081990]
AC50 0.0154HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set3 [AID588553, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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4
[SID125081990]
AC50 0.0285HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set4 [AID588548, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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5
[SID125081990]
AC50 0.0294HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID588754, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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6
[SID125081990]
AbsAC40_uM 0.145HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID588810, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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7
[SID125081990]
AC50 70HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID602126, Type: confirmatory]
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8
[SID125081990]
AC50 HDL Counter Assay: Tf Endo Assay Measured in Cell-Based System Using Plate Reader - 2085-04_Inhibitor_Dose_DryPowder_Activity [AID602134, Type: confirmatory]
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9
[SID125081990]
AC50 DiI Quencher Assay Measured in Biochemical System Using Plate Reader - 2085-08_Inhibitor_Dose_DryPowder_Activity [AID588403, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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10
[SID125081990]
AC50 HDL Uptake counterscreen Measured in Cell-Based System Using Plate Reader - 2085-07_Inhibitor_Dose_DryPowder_Activity [AID588825, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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11
[SID125081990]
AC50 HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set3 [AID588826, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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12
[SID125081990]
AC50 HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set2 [AID588829, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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