BRD-K93724056-001-01-9 (CID 53347941) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(5)
 
 
Inactive(2)
 
 
Top Targets:
CD36(6)
 
 
 
BioAssay Types:
Confirmatory(7)
 
 
 
BioActivity Types:
AC50(6)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 7    Data Row: 7   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125082028]
AC50 0.00433HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set2 [AID588392, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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2
[SID125082028]
AC50 0.0295HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set4 [AID588548, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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3
[SID125082028]
AC50 0.0426HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set5 [AID588754, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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4
[SID125082028]
AC50 0.0529HTS using DiI-HDL to assay lipid transfer in ldlA[SR-BI] cells Measured in Cell-Based System Using Plate Reader - 2085-01_Inhibitor_Dose_DryPowder_Activity_Set3 [AID588553, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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5
[SID125082028]
AbsAC40_uM 0.382HDL Orthogonal Assay: Alexa 488-HDL Measured in Cell-Based System Using Plate Reader - 2085-03_Inhibitor_Dose_DryPowder_Activity_Set2 [AID588810, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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6
[SID125082028]
AC50 70HDL Counter Assay: 3/24 Cytotox Measured in Cell-Based System Using Plate Reader - 2085-02_Inhibitor_Dose_DryPowder_Activity_Set5 [AID602126, Type: confirmatory]
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7
[SID125082028]
AC50 DiI Quencher Assay Measured in Biochemical System Using Plate Reader - 2085-08_Inhibitor_Dose_DryPowder_Activity [AID588403, Type: confirmatory]Scarb1 gene product [Mus musculus] [gi:14389423]
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