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VU0458298-1 (CID 53347901) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Top Targets:
KCNQ channel(2)
 
 
BioAssay Types:
Confirmatory(1)
 
 
BioActivity Types:
IC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2    Data Row: 2   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID125081894]
IC50 0.26063SAR analysis for compounds that activate KCNQ1 potassium channels in the KCNQ1 expressing cells on automated patch clamp [AID588673, Type: confirmatory]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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2
[SID125081894]
Manual patch clamp assay to confirm a potent KCNQ1 activator [AID602120, Type: other]potassium voltage-gated channel subfamily KQT member 1 isoform 1 [Homo sapiens] [gi:32479527]
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