ML277
(CID
53347901
) -
BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(
2
)
Top Targets:
KCNQ channel(
2
)
BioAssay Types:
Confirmatory(
1
)
BioActivity Types:
IC50(
1
)
SAR
Target summary
Data download
Chemical Probe
Active
Inactive
Inconclusive
Unspecified
Total Bioassays: 2 Data Row: 2 Total Pages: 1
Sort:
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#
Substance
Activity
BioAssay
Target
Links
Outcome
Type
Value [μM]
1
[SID
125081894
]
Active
IC50
0.26063
SAR analysis for compounds that activate KCNQ1 potassium channels in the KCNQ1 expressing cells on automated patch clamp [AID
588673
, Type: confirmatory]
KCNQ1 gene product [Homo sapiens] [gi:
32479527
]
View
X
Row No.
1
Structure
Substance
SID
125081894
CID
53347901
Outcome
Active
IC50
0.26063 [uM]
BioAssay
SAR analysis for compounds that activate KCNQ1 potassium channels in the KCNQ1 expressing cells on automated patch clamp
AID
588673
BioAssay type
confirmatory
Target
KCNQ1 gene product [Homo sapiens] [gi:
32479527
]
PubMed
Data Table
2
[SID
125081894
]
Active
Manual patch clamp assay to confirm a potent KCNQ1 activator [AID
602120
, Type: other]
KCNQ1 gene product [Homo sapiens] [gi:
32479527
]
View
X
Row No.
2
Structure
Substance
SID
125081894
CID
53347901
Outcome
Active
BioAssay
Manual patch clamp assay to confirm a potent KCNQ1 activator
AID
602120
BioAssay type
other
Target
KCNQ1 gene product [Homo sapiens] [gi:
32479527
]
PubMed
Data Table
Chemical Probe 
Active 
Inactive 
Inconclusive 
Unspecified 
