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MLS001066030 (CID 53313061) - Compound BioActivity Data
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BioActivity Outcomes:
Active(25)
 
 
Inactive(343)
 
 
Inconclusive(32)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(27)
 
 
Peptidase C48(11)
 
 
 
RasGEF(4)
 
 
Esterase lipa..(4)
 
 
 
ABCC CFTR1(4)
 
 
BioAssay Types:
Screening(285)
 
 
 
 
Confirmatory(101)
 
 
 
 
 
Literature(11)
 
 
 
BioActivity Types:
Potency(86)
 
 
 
 
 
IC50(11)
 
 
 
 
AC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 361    Data Row: 401   Total Pages: 21   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID74373569]
IC50_Mean 7.22Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay [AID488904, Type: confirmatory]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
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2
[SID74373569]
IC50_Mean 9.6Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488921, Type: confirmatory]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
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3
[SID74373569]
IC50_Mean 12.9Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488901, Type: confirmatory]caspase-3 preproprotein [Homo sapiens] [gi:14790119]
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4
[SID74373569]
Potency 14.1254qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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5
[SID74373569]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID74373569]
Potency 16.3601A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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7
[SID74373569]
IC50_Mean 18Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay [AID488903, Type: confirmatory]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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8
[SID74373569]
Potency 23.1093qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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9
[SID74373569]
Fluorescence polarization-based biochemical high throughput confirmation assay to identify inhibitors of alpha/beta hydrolase domain containing 4 (ABHD4). [AID720658, Type: screening]abhydrolase domain-containing protein 4 isoform 1 [Mus musculus] [gi:326937491]
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10
[SID74373569]
Fluorescence polarization-based biochemical high throughput primary assay to identify inhibitors of alpha/beta hydrolase domain containing 4 (ABHD4). [AID720543, Type: screening]abhydrolase domain-containing protein 4 isoform 1 [Mus musculus] [gi:326937491]
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11
[SID74373569]
HTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 8 (SENP8) [AID2540, Type: screening]sentrin-specific protease 8 [Homo sapiens] [gi:262118306]
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12
[SID74373569]
Screen for inhibitors of the SWI/SNF chromatin remodeling complex (esBAF) in mouse embryonic stem cells with Luciferase reporter assay Measured in Cell-Based System Using Plate Reader - 2141-01_Inhibitor_SinglePoint_HTS_Activity [AID602393, Type: screening]transcription activator BRG1 isoform 1 [Mus musculus] [gi:291463269]
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13
[SID74373569]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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14
[SID74373569]
Fluorescence-based biochemical high throughput confirmation assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID651616, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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15
[SID74373569]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 7 (SENP7) [AID434973, Type: screening]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
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16
[SID74373569]
Single concentration confirmation of uHTS for inhibitors of Sentrin-specific protease 7 (SENP7) using a Luminescent assay [AID488917, Type: screening]SUMO1/sentrin specific peptidase 7 [Homo sapiens] [gi:120538355]
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17
[SID74373569]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]protein Mdm4 isoform 1 [Homo sapiens] [gi:88702791]
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18
[SID74373569]
uHTS for identification of Inhibitors of Mdm2/MdmX interaction in luminescent format. [AID485346, Type: screening]E3 ubiquitin-protein ligase Mdm2 isoform a [Homo sapiens] [gi:89993689]
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19
[SID74373569]
Luminescence-based cell-based primary high throughput screening assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) [AID652126, Type: screening]Protein DAF-12, isoform a [Caenorhabditis elegans] [gi:71987181]
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20
[SID74373569]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
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