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AGN-PC-09QAV6 (CID 53308666) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(4)
 
 
Top Targets:
M1 APN 1(1)
 
 
PTZ00371(1)
 
 
Peptidase M17(1)
 
 
BioAssay Types:
Confirmatory(5)
 
 
 
BioActivity Types:
IC50(4)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124767867]
Average CC50 7.78Vero Cytoxicity Assay: A Cell Based Secondary Assay To Explore Cytotoxicity of Compounds that Inhibit Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) [AID588714, Type: confirmatory]
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2
[SID124767867]
Average hM18AAP IC50 Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the human M18 Aspartyl Aminopeptidase (hM18AAP) [AID588696, Type: confirmatory]Chain A, Crystal Structure Of Human Aspartyl Aminopeptidase (Dnpep), In Complex With Aspartic Acid Hydroxamate [gi:291191219]
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3
[SID124767867]
Average M17 IC50 Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M17 Leucine Aminopeptidase (PFM17LAP) [AID588679, Type: confirmatory]M17 leucyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23497510]
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4
[SID124767867]
Average IC50 QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PFM18AAP) [AID588678, Type: confirmatory]M18 aspartyl aminopeptidase [Plasmodium falciparum 3D7] [gi:23505220]
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5
[SID124767867]
Average PFM1AAP IC50 Counterscreen for inhibitors of PFM18AAP: QFRET-based biochemical high throughput dose response assay for inhibitors of the Plasmodium falciparum M1AAP (PFM1AAP) [AID588680, Type: confirmatory]m1-family aminopeptidase [Plasmodium falciparum 3D7] [gi:23615263]
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