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AGN-PC-09PPOS (CID 53299544) - Compound BioActivity Data
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BioActivity Outcomes:
Active(31)
 
 
Inactive(465)
 
 
Inconclusive(21)
 
 
Unspecified(1)
 
 
Top Targets:
7tm 4(33)
 
 
 
RasGEF(8)
 
 
 
Esterase lipa..(7)
 
 
 
Toxin trans(6)
 
 
NR DBD CAR(6)
 
 
BioAssay Types:
Screening(383)
 
 
 
Confirmatory(111)
 
 
 
 
 
Literature(20)
 
 
BioActivity Types:
Potency(102)
 
 
 
 
 
IC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 357    Data Row: 518   Total Pages: 26   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID74373555]
Potency 7.0795qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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2
[SID74373555]
Potency 11.2202qHTS for Inhibitors of TGF-b: Cytotox Counterscreen [AID588856, Type: confirmatory]
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3
[SID74373555]
Potency 11.2202qHTS for Inhibitors of TGF-b [AID588855, Type: confirmatory]Smad3 [Homo sapiens] [gi:18418623]
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4
[SID74373555]
Potency 14.581qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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5
[SID74373555]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID74373555]
Potency 20.5962qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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7
[SID74373555]
Potency 20.5962A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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8
[SID74373555]
Potency 23.1093qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line [AID686971, Type: confirmatory]
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9
[SID124753352]
Potency 23.485qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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10
[SID74373555]
Potency 25.1189qHTS for Stage-Specific Inhibitors of Vaccinia Orthopoxvirus: mCherry Reporter Primary qHTS [AID720579, Type: confirmatory]67.9K protein [Vaccinia virus] [gi:222762]
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11
[SID124753352]
Potency 26.3506qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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12
[SID124753352]
Potency 27.2824qHTS Assay for Activators of ClpP [AID651965, Type: confirmatory]ClpP [Bacillus subtilis] [gi:2668494]
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13
[SID74373555]
Potency 31.6228qHTS for Inhibitors of ATXN expression [AID651635, Type: confirmatory]ataxin-2 [Homo sapiens] [gi:171543895]
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14
[SID74373555]
Potency 39.8107qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS [AID624288, Type: confirmatory]Guanine nucleotide-binding protein G(s) subunit alpha isoforms short [gi:52000961]
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15
[SID74373555]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human cholinergic receptor, muscarinic 4 (CHRM4) [AID624125, Type: screening]muscarinic acetylcholine receptor M4 [Homo sapiens] [gi:52426748]
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16
[SID74373555]
qHTS of D3 Dopamine Receptor Agonist: qHTS [AID652048, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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17
[SID74373555]
qHTS of D3 Dopamine Receptor Potentiators: qHTS [AID652051, Type: screening]D(3) dopamine receptor isoform e [Homo sapiens] [gi:89191863]
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18
[SID74373555]
Fluorescence-based cell-based primary high throughput screening assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1) [AID624466, Type: screening]trace amine-associated receptor 1 [Homo sapiens] [gi:21264324]
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19
[SID74373555]
qHTS for Inhibitors of Inflammasome Signaling: IL-1-beta AlphaLISA Primary Screen [AID743279, Type: screening]interleukin-1 beta proprotein [Homo sapiens] [gi:10835145]
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20
[SID74373555]
Fluorescence-based biochemical primary high throughput screening assay to identify inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis [AID588726, Type: screening]fructose-bisphosphate aldolase [Mycobacterium tuberculosis H37Rv] [gi:15607504]
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