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GW632046X (CID 5329849) - Compound BioActivity Data
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BioActivity Outcomes:
Active(6)
 
 
Inactive(6)
 
 
Inconclusive(3)
 
 
Unspecified(456)
 
 
Top Targets:
PTKc Abl(16)
 
 
PTKc EGFR(10)
 
 
PKc like(10)
 
 
STKc MARK(8)
 
 
PTKc PDGFR al..(8)
 
 
BioAssay Types:
Literature(7)
 
 
 
 
Confirmatory(5)
 
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
IC50(4)
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 469    Data Row: 471   Total Pages: 24   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID124350137]
Potency 0.5799qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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2
[SID103465244]
IC50 0.87Inhibition of human Vascular endothelial growth factor receptor 2 [AID241758, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
View
3
[SID103465244]
IC50 1.7Inhibition of VEGF-induced proliferation of human umbilical vein endothelial cells [AID248240, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
View
4
[SID103465244]
IC50 1.7Inhibition of VEGF-induced proliferation of human umbilical vein endothelial cells [AID248240, Type: Literature]Vascular endothelial growth factor receptor 1 [gi:143811474]
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5
[SID103465244]
IC50 1.7Inhibition of VEGF-induced proliferation of human umbilical vein endothelial cells [AID248240, Type: Literature]Vascular endothelial growth factor receptor 3 [gi:357529070]
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6
[SID134352859]
A screen for small compounds that change glucocorticoid sensitivity in NFkB suppression [AID624486, Type: other]
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7
[SID103465244]
AC50 0.5799GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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8
[SID103465244]
AC50 GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
View
9
[SID103465244]
GSK_PKIS: PDGFRB mean inhibition at 0.1 uM [Nanosyn] [AID651298, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
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10
[SID103465244]
GSK_PKIS: PDGFRB mean inhibition at 1 uM [Nanosyn] [AID651299, Type: other]Platelet-derived growth factor receptor beta [gi:129890]
View
11
[SID103465244]
GSK_PKIS: PDGFRA mean inhibition at 0.1 uM [Nanosyn] [AID651290, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
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12
[SID103465244]
GSK_PKIS: PDGFRA mean inhibition at 1 uM [Nanosyn] [AID651291, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
13
[SID103465244]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651292, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
14
[SID103465244]
GSK_PKIS: PDGFRA (D842V mutant) mean inhibition at 1 uM [Nanosyn] [AID651293, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
15
[SID103465244]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651294, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
16
[SID103465244]
GSK_PKIS: PDGFRA (T674I mutant) mean inhibition at 1 uM [Nanosyn] [AID651295, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
17
[SID103465244]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 0.1 uM [Nanosyn] [AID651296, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
18
[SID103465244]
GSK_PKIS: PDGFRA (V561D mutant) mean inhibition at 1 uM [Nanosyn] [AID651297, Type: other]Platelet-derived growth factor receptor alpha [gi:129892]
View
19
[SID103465244]
GSK_PKIS: CDK3/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651168, Type: other]Cyclin-dependent kinase 3 [gi:231726]
View
20
[SID103465244]
GSK_PKIS: CDK3/cyclinE mean inhibition at 1 uM [Nanosyn] [AID651169, Type: other]Cyclin-dependent kinase 3 [gi:231726]
View