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GW809897X (CID 5329831) - Compound BioActivity Data
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BioActivity Outcomes:
Active(4)
 
 
Inactive(9)
 
 
Inconclusive(1)
 
 
Unspecified(456)
 
 
Top Targets:
PKc(42)
 
 
PKc like(42)
 
 
STKc AGC(16)
 
 
PTKc Abl(16)
 
 
PTKc Src like(11)
 
 
 
BioAssay Types:
Literature(5)
 
 
 
Confirmatory(5)
 
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
AC50(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 470    Data Row: 470   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103457339]
IC50 0.029Inhibitory concentration against human umbilical vein endothelial cells (HUVECs) induced by VEGF [AID248167, Type: Literature]
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2
[SID103457339]
IC50 0.065Inhibitory concentration against human VEGFR2 kinase [AID240506, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
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3
[SID124350076]
Potency 0.5799qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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4
[SID124350076]
Potency 1.4631qHTS for small molecule inhibitors of Yes1 kinase: Primary Screen [AID686947, Type: Literature]tyrosine-protein kinase Yes [Homo sapiens] [gi:4885661]
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5
[SID103457339]
AC50 0.5799GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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6
[SID103457339]
GSK_PKIS: CK1-g2 mean inhibition at 0.1 uM [Nanosyn] [AID651158, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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7
[SID103457339]
GSK_PKIS: CK1-g2 mean inhibition at 1 uM [Nanosyn] [AID651159, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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8
[SID103457339]
GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] [AID651018, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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9
[SID103457339]
GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] [AID651019, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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10
[SID103457339]
GSK_PKIS: MST4 mean inhibition at 0.1 uM [Nanosyn] [AID651358, Type: other]Serine/threonine-protein kinase MST4 [gi:73621232]
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11
[SID103457339]
GSK_PKIS: MST4 mean inhibition at 1 uM [Nanosyn] [AID651359, Type: other]Serine/threonine-protein kinase MST4 [gi:73621232]
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12
[SID103457339]
GSK_PKIS: CDK6/cyclinD3 mean inhibition at 0.1 uM [Nanosyn] [AID651174, Type: other]Cyclin-dependent kinase 6 [gi:266423]
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13
[SID103457339]
GSK_PKIS: CDK6/cyclinD3 mean inhibition at 1 uM [Nanosyn] [AID651175, Type: other]Cyclin-dependent kinase 6 [gi:266423]
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14
[SID103457339]
GSK_PKIS: AKT3 mean inhibition at 0.1 uM [Nanosyn] [AID651022, Type: other]RAC-gamma serine/threonine-protein kinase [gi:12643943]
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15
[SID103457339]
GSK_PKIS: AKT3 mean inhibition at 1 uM [Nanosyn] [AID651023, Type: other]RAC-gamma serine/threonine-protein kinase [gi:12643943]
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16
[SID103457339]
GSK_PKIS: TYK2 mean inhibition at 0.1 uM [Nanosyn] [AID651336, Type: other]Non-receptor tyrosine-protein kinase TYK2 [gi:56405328]
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17
[SID103457339]
GSK_PKIS: TYK2 mean inhibition at 1 uM [Nanosyn] [AID651447, Type: other]Non-receptor tyrosine-protein kinase TYK2 [gi:56405328]
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18
[SID103457339]
GSK_PKIS: MER mean inhibition at 0.1 uM [Nanosyn] [AID651284, Type: other]Tyrosine-protein kinase Mer [gi:160332297]
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19
[SID103457339]
GSK_PKIS: MER mean inhibition at 1 uM [Nanosyn] [AID651285, Type: other]Tyrosine-protein kinase Mer [gi:160332297]
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20
[SID103457339]
GSK_PKIS: Mer Kinase % inhibition at 10 uM [UNC Frye lab] [AID651544, Type: other]Tyrosine-protein kinase Mer [gi:160332297]
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