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N,5-diphenyl-1,3-oxazol-2-amine (CID 5329404) - Compound BioActivity Data
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BioActivity Outcomes:
Active(9)
 
 
Inactive(7)
 
 
Inconclusive(2)
 
 
Unspecified(456)
 
 
Top Targets:
PKc(42)
 
 
PKc like(42)
 
 
PTKc Abl(16)
 
 
STKc AGC(16)
 
 
PTKc Src like(11)
 
 
 
BioAssay Types:
Literature(9)
 
 
 
 
Confirmatory(5)
 
 
 
 
BioActivity Types:
Potency(7)
 
 
 
 
IC50(6)
 
 
AC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 472    Data Row: 474   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103316127]
IC50 0.134Inhibitory activity towards vascular endothelial growth factor receptor 2 [AID216645, Type: Literature]
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2
[SID124350051]
Potency 0.259qHTS Assay for Inhibitors of Firefly Luciferase from the GSK Published Protein Kinase Inhibitor Set [AID652016, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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3
[SID103316127]
IC50 1.2Inhibition of human Vascular endothelial growth factor receptor 2 [AID241758, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
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4
[SID103316127]
IC50 3Inhibition of VEGF-induced proliferation of human umbilical vein endothelial cells [AID248240, Type: Literature]Vascular endothelial growth factor receptor 2 [gi:9087218]
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5
[SID103316127]
IC50 3Inhibition of VEGF-induced proliferation of human umbilical vein endothelial cells [AID248240, Type: Literature]Vascular endothelial growth factor receptor 1 [gi:143811474]
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6
[SID103316127]
IC50 3Inhibition of VEGF-induced proliferation of human umbilical vein endothelial cells [AID248240, Type: Literature]Vascular endothelial growth factor receptor 3 [gi:357529070]
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7
[SID124350051]
Potency 4.9917qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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8
[SID103316127]
IC50 24Inhibition of basic FGF-induced proliferation of human umbilical vein endothelial cells [AID248370, Type: Literature]
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9
[SID134352700]
A screen for small compounds that change glucocorticoid sensitivity in NFkB suppression [AID624486, Type: other]
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10
[SID103316127]
AC50 0.259GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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11
[SID103316127]
GSK_PKIS: CK1-g2 mean inhibition at 0.1 uM [Nanosyn] [AID651158, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
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12
[SID103316127]
GSK_PKIS: CK1-g2 mean inhibition at 1 uM [Nanosyn] [AID651159, Type: other]Casein kinase I isoform gamma-2 [gi:3024060]
View
13
[SID103316127]
GSK_PKIS: AKT1 mean inhibition at 0.1 uM [Nanosyn] [AID651018, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
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14
[SID103316127]
GSK_PKIS: AKT1 mean inhibition at 1 uM [Nanosyn] [AID651019, Type: other]RAC-alpha serine/threonine-protein kinase [gi:60391226]
View
15
[SID103316127]
GSK_PKIS: MST4 mean inhibition at 0.1 uM [Nanosyn] [AID651358, Type: other]Serine/threonine-protein kinase MST4 [gi:73621232]
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16
[SID103316127]
GSK_PKIS: MST4 mean inhibition at 1 uM [Nanosyn] [AID651359, Type: other]Serine/threonine-protein kinase MST4 [gi:73621232]
View
17
[SID103316127]
GSK_PKIS: CDK2/cyclinA mean inhibition at 0.1 uM [Nanosyn] [AID651164, Type: other]Cyclin-dependent kinase 2 [gi:116051]
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18
[SID103316127]
GSK_PKIS: CDK2/cyclinA mean inhibition at 1 uM [Nanosyn] [AID651165, Type: other]Cyclin-dependent kinase 2 [gi:116051]
View
19
[SID103316127]
GSK_PKIS: CDK2/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651166, Type: other]Cyclin-dependent kinase 2 [gi:116051]
View
20
[SID103316127]
GSK_PKIS: CDK2/cyclinE mean inhibition at 1 uM [Nanosyn] [AID651167, Type: other]Cyclin-dependent kinase 2 [gi:116051]
View