CHEMBL1914580 (CID 53257379) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(4)
 
 
Inactive(1)
 
 
Inconclusive(2)
 
 
Unspecified(1)
 
 
BioAssay Types:
Literature(8)
 
 
 
 
 
BioActivity Types:
EC50(2)
 
 
 
IC50(1)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 8    Data Row: 8   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID136935305]
IC50 10.3Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution assay [AID630382, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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2
[SID136935305]
IC50 10.3Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution assay [AID630382, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
3
[SID136935305]
IC50 10.3Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution assay [AID630382, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
4
[SID136935305]
EC50 11.1Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay [AID630439, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
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5
[SID136935305]
EC50 11.1Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay [AID630439, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
6
[SID136935305]
EC50 11.1Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay [AID630439, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
7
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of GPR35 antagonist SPB05142 [AID630441, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
8
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of GPR35 antagonist SPB05142 [AID630441, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
9
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of GPR35 antagonist SPB05142 [AID630441, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
10
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of 64 uM GPR35 antagonist SPB05142 [AID630442, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
11
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of 64 uM GPR35 antagonist SPB05142 [AID630442, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
12
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay in presence of 64 uM GPR35 antagonist SPB05142 [AID630442, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
13
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay relative to zaprinast [AID630381, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
14
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay relative to zaprinast [AID630381, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
15
[SID136935305]
 Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assay relative to zaprinast [AID630381, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
16
[SID136935305]
 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation up to 128 uM after 5 hrs by tango beta-arrestin translocation reporter assay [AID630388, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
17
[SID136935305]
 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation up to 128 uM after 5 hrs by tango beta-arrestin translocation reporter assay [AID630388, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
18
[SID136935305]
 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation up to 128 uM after 5 hrs by tango beta-arrestin translocation reporter assay [AID630388, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
19
[SID136935305]
EC50 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay [AID630386, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
20
[SID136935305]
EC50 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay [AID630386, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
21
[SID136935305]
EC50 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay [AID630386, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
22
[SID136935305]
 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay relative to zaprinast [AID630387, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
23
[SID136935305]
 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay relative to zaprinast [AID630387, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View
24
[SID136935305]
 Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcriptional activation after 5 hrs by tango beta-arrestin translocation reporter assay relative to zaprinast [AID630387, Type: Literature]G-protein coupled receptor 35 [gi:68068087]
View