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AGN-PC-074HGW (CID 53239978) - Compound BioActivity Data
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BioActivity Outcomes:
Active(2)
 
 
Unspecified(457)
 
 
Top Targets:
PKc like(42)
 
 
PKc(42)
 
 
STKc AGC(16)
 
 
PTKc Abl(16)
 
 
PTKc EGFR(10)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
AC50(2)
 
 
IC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 459    Data Row: 459   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID134441818]
IC50 0.046Inhibition of cRaf1 kinase in cascade assay [AID220315, Type: Literature]
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2
[SID134441818]
IC50 0.046Inhibition of Raf1 kinase [AID322453, Type: Literature]
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3
[SID134441818]
AC50 16.3432GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS] [AID720834, Type: Literature]Renilla-luciferin 2-monooxygenase [gi:126502]
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4
[SID134441818]
AC50 18.3374GSK_PKIS: Inhibition of Firefly Luciferase (Data from PubChem: AID 652016) [NIH NCATS] [AID720835, Type: Literature]Luciferin 4-monooxygenase [gi:126501]
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5
[SID134441818]
GSK_PKIS: PIP5K1 (Caliper assay) % inhibition at 5 uM [UNC Frye lab] [AID651545, Type: other]
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6
[SID134441818]
GSK_PKIS: CDK2/cyclinA mean inhibition at 0.1 uM [Nanosyn] [AID651164, Type: other]Cyclin-dependent kinase 2 [gi:116051]
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7
[SID134441818]
GSK_PKIS: CDK2/cyclinA mean inhibition at 1 uM [Nanosyn] [AID651165, Type: other]Cyclin-dependent kinase 2 [gi:116051]
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8
[SID134441818]
GSK_PKIS: CDK2/cyclinE mean inhibition at 0.1 uM [Nanosyn] [AID651166, Type: other]Cyclin-dependent kinase 2 [gi:116051]
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9
[SID134441818]
GSK_PKIS: CDK2/cyclinE mean inhibition at 1 uM [Nanosyn] [AID651167, Type: other]Cyclin-dependent kinase 2 [gi:116051]
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10
[SID134441818]
GSK_PKIS: ERBB2 mean inhibition at 0.1 uM [Nanosyn] [AID651424, Type: other]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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11
[SID134441818]
GSK_PKIS: ERBB2 mean inhibition at 1 uM [Nanosyn] [AID651425, Type: other]Receptor tyrosine-protein kinase erbB-2 [gi:119533]
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12
[SID134441818]
GSK_PKIS: MAPK1 mean inhibition at 0.1 uM [Nanosyn] [AID651196, Type: other]Mitogen-activated protein kinase 1 [gi:119554]
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13
[SID134441818]
GSK_PKIS: MAPK1 mean inhibition at 1 uM [Nanosyn] [AID651197, Type: other]Mitogen-activated protein kinase 1 [gi:119554]
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14
[SID134441818]
GSK_PKIS: FGFR2 mean inhibition at 0.1 uM [Nanosyn] [AID651434, Type: other]Fibroblast growth factor receptor 2 [gi:120049]
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15
[SID134441818]
GSK_PKIS: FGFR2 mean inhibition at 1 uM [Nanosyn] [AID651435, Type: other]Fibroblast growth factor receptor 2 [gi:120049]
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16
[SID134441818]
GSK_PKIS: FGFR3 mean inhibition at 0.1 uM [Nanosyn] [AID651436, Type: other]Fibroblast growth factor receptor 3 [gi:120050]
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17
[SID134441818]
GSK_PKIS: FGFR3 mean inhibition at 1 uM [Nanosyn] [AID651437, Type: other]Fibroblast growth factor receptor 3 [gi:120050]
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18
[SID134441818]
GSK_PKIS: IGF1R mean inhibition at 0.1 uM [Nanosyn] [AID651252, Type: other]Insulin-like growth factor 1 receptor [gi:124240]
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19
[SID134441818]
GSK_PKIS: IGF1R mean inhibition at 1 uM [Nanosyn] [AID651253, Type: other]Insulin-like growth factor 1 receptor [gi:124240]
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20
[SID134441818]
GSK_PKIS: PKA mean inhibition at 0.1 uM [Nanosyn] [AID651040, Type: other]cAMP-dependent protein kinase catalytic subunit alpha [gi:125205]
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