CHEMBL1770198 (CID 53231533) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Unspecified(3)
 
 
Top Targets:
Esterase lipa..(2)
 
 
BioAssay Types:
Literature(5)
 
 
 
BioActivity Types:
IC50(3)
 
 
 
SAR
Target summary
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 5    Data Row: 5   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131275459]
IC50 0.933Inhibition of electric eel AChE by Ellman's method [AID594254, Type: Literature]Acetylcholinesterase [gi:14916521]
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2
[SID131275459]
IC50 0.972Inhibition of equine serum BChE by Ellman's method [AID594255, Type: Literature]Cholinesterase [gi:21362409]
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3
[SID131275459]
IC50 25Cytotoxicity against human SH-SY5Y cells assessed as cell viability after 48 hrs by MTT assay [AID594251, Type: Literature]
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4
[SID131275459]
 Inhibition of amyloid beta (1 to 42) aggregation assessed as inhibition of fibril formation at 10 uM by thioflavin-T fluorescent dye assay [AID594253, Type: Literature]
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5
[SID131275459]
 Selectivity ratio of IC50 for equine serum BChE to IC50 for electric eel AChE [AID594252, Type: Literature]
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