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7-hydroxy-4-propyl-2H-chromen-2-one (CID 5322246) - Compound BioActivity Data
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BioActivity Outcomes:
Active(1)
 
 
Inactive(5)
 
 
Unspecified(9)
 
 
Top Targets:
14-3-3 gamma(1)
 
 
RNase H(1)
 
 
G glu transpe..(1)
 
 
17beta-HSD1 l..(1)
 
 
MarR(1)
 
 
BioAssay Types:
Literature(10)
 
 
 
Screening(3)
 
 
BioActivity Types:
IC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 15   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103716287]
IC50 0.059Inhibition of human 17beta-HSD3 expressed in HeLa cells [AID452459, Type: Literature]Testosterone 17-beta-dehydrogenase 3 [gi:1169300]
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2
[SID103716287]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced NO production at 10 uM by Griess reaction [AID613464, Type: Literature]
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3
[SID103716287]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced NO production at 100 uM by Griess reaction [AID613465, Type: Literature]
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4
[SID103716287]
Inhibition of LPS-stimulated iNOS protein expression in mouse J774 cells at 10 uM by RT-PCR analysis [AID613466, Type: Literature]
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5
[SID103716287]
Inhibition of LPS-stimulated iNOS protein expression in mouse J774 cells at 100 uM by RT-PCR analysis [AID613467, Type: Literature]
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6
[SID103716287]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced IL-6 production at 10 uM by ELISA [AID613470, Type: Literature]
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7
[SID103716287]
Antiinflammatory activity in mouse J774 cells assessed as inhibition of LPS-induced IL-6 production at 100 uM by ELISA [AID613471, Type: Literature]
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8
[SID103716287]
Inhibition of LPS-stimulated COX2 protein expression in mouse J774 cells at 10 uM by chemiluminescence assay [AID613472, Type: Literature]
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9
[SID103716287]
Inhibition of LPS-stimulated COX2 protein expression in mouse J774 cells at 100 uM by chemiluminescence assay [AID613473, Type: Literature]
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10
[SID103716287]
Cytotoxicity against mouse J774 cells at 100 uM by XTT assay [AID613474, Type: Literature]
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11
[SID7996451]
Formylpeptide Receptor Ligand Binding Assay [AID362, Type: screening]fMet-Leu-Phe receptor [Homo sapiens] [gi:4503779]
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12
[SID24336702]
HTS for 14-3-3 protein interaction modulators [AID422, Type: screening]14-3-3 protein gamma [Homo sapiens] [gi:21464101]
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13
[SID8056548]
HIV-1 RNase H Inhibition [AID372, Type: screening]Chain A, Solution Structure Of The Rnase H Domain Of The Hiv-1 Reverse Transcriptase In The Presence Of Magnesium [gi:28949057]
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14
[SID92260152]
A screen for compounds that inhibit the CapD enzyme of Bacillus anthracis [AID492967, Type: other]gamma-glutamyltranspeptidase [Bacillus anthracis str. 'Ames Ancestor'] [gi:47566732]
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15
[SID92260152]
A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID602314, Type: other]MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:151220867]
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