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15-deoxyprostaglandin J2 (CID 5311211) - Compound BioActivity Data
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BioActivity Outcomes:
Active(22)
 
 
Inactive(130)
 
 
Inconclusive(23)
 
 
Unspecified(4)
 
 
Top Targets:
HELICc(8)
 
 
 
 
Tubulin-bindi..(8)
 
 
 
 
NR LBD TR(8)
 
 
PLDc mTdp1 2(6)
 
 
 
 
GH27(6)
 
 
BioAssay Types:
Confirmatory(147)
 
 
 
 
 
Screening(14)
 
 
Literature(14)
 
 
 
 
BioActivity Types:
Potency(135)
 
 
 
 
IC50(2)
 
 
Kd(1)
 
 
EC50(1)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 78    Data Row: 179   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103640339]
IC50 0.3Inhibition of mPGES1 [AID405533, Type: Literature]
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2
[SID26754844]
Potency 1.4125Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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3
[SID103640339]
Kd 2Binding affinity to PPARgamma [AID677050, Type: Literature]
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4
[SID103640339]
IC50 2.2Suppression of LPS/IFN-gamma-stimulated NO production in mouse RAW264.7 cells [AID348772, Type: Literature]
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5
[SID26754843]
Potency 3.1623qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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6
[SID103640339]
EC50 5.6Activation of TRPA1 channel [AID482142, Type: Literature]
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7
[SID26754843]
Potency 12.5893Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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8
[SID26754844]
Potency 15.8489qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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9
[SID26754844]
Potency 15.8489qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding [AID1460, Type: confirmatory]Microtubule-associated protein tau [Homo sapiens] [gi:92096784]
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10
[SID26754843]
Potency 17.7828qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1) [AID485290, Type: confirmatory]Chain A, Crystal Structure Of Human Tyrosyl-Dna Phosphodiesterase (Tdp1) [gi:20150581]
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11
[SID26754843]
Potency 19.9526qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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12
[SID26754845]
Potency 19.9526Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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13
[SID26754844]
Potency 22.3872qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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14
[SID26754842]
Potency 28.1838Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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15
[SID26754843]
Potency 28.1838qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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16
[SID26754844]
Potency 35.4813qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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17
[SID26754844]
Potency 56.2341qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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18
[SID103640339]
Binding affinity to PPARgamma in C57BL/6J mouse macrophages assessed as increase in CD36 mRNA level at 5 uM after 48 hrs by real-time PCR analysis [AID468334, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432235]
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19
[SID103640339]
Binding affinity to PPARgamma in C57BL/6J mouse macrophages assessed as increase in Cpt1alpha mRNA level at 5 uM after 48 hrs by real-time PCR analysis [AID468335, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432235]
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20
[SID103640339]
Inhibition of human FLAG-tagged IKK-beta expressed in HEK293 cells at 50 uM by Western blot analysis in presence of ATP [AID430850, Type: Literature]Inhibitor of nuclear factor kappa-B kinase subunit beta [gi:14285497]
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