Bookmark and Share
BRN 1252082 (CID 5310669) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(34)
 
 
Inactive(786)
 
 
Inconclusive(22)
 
 
Unspecified(9)
 
 
Top Targets:
7TM GPCR Srx(26)
 
 
7TM GPCR Srsx(21)
 
 
NR LBD PPAR(15)
 
 
 
 
alkPPc(14)
 
 
Tryp SPc(13)
 
 
BioAssay Types:
Screening(573)
 
 
 
 
Confirmatory(235)
 
 
 
 
 
Literature(24)
 
 
 
 
BioActivity Types:
Potency(165)
 
 
 
 
 
IC50(50)
 
 
 
EC50(17)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 778    Data Row: 851   Total Pages: 43   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7973370]
Potency 0.9178qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. [AID588397, Type: confirmatory]
View
2
[SID7973370]
Potency 2.5119qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
3
[SID7973370]
Potency 2.5119qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
4
[SID7973370]
Potency 3.1623qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
View
5
[SID7973370]
Potency 3.5481qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
View
6
[SID7973370]
Potency 11.2202qHTS Assay to Identify Small Molecule Activators of BRCA1 Expression [AID624202, Type: confirmatory]BRCA1 [Homo sapiens] [gi:1698399]
View
7
[SID7973370]
Potency 13.4591qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
8
[SID103699275]
EC50 15.38Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay [AID736343, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
View
9
[SID103699275]
EC50 15.38Agonist activity at human PPARgamma assessed as luciferase activity by transactivation assay [AID439369, Type: Literature]Peroxisome proliferator-activated receptor gamma [gi:13432234]
View
10
[SID103699275]
EC50 23.1Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay [AID736344, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
11
[SID103699275]
EC50 24.39Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay [AID736342, Type: Literature]Peroxisome proliferator-activated receptor delta [gi:417522]
View
12
[SID7973370]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
13
[SID7973370]
Potency 31.6228qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
View
14
[SID103699275]
EC50 33.13Agonist activity at human PPARalpha assessed as luciferase activity by transactivation assay [AID439370, Type: Literature]Peroxisome proliferator-activated receptor alpha [gi:3041727]
View
15
[SID7973370]
Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Primary Screen [AID1456, Type: other]electroneutral potassium-chloride cotransporter KCC2 [Homo sapiens] [gi:12003227]
View
16
[SID7973370]
Single concentration confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay [AID488918, Type: screening]caspase-3 preproprotein [Homo sapiens] [gi:14790119]
View
17
[SID7973370]
uHTS Luminescent assay for identification of inhibitors of Sentrin-specific protease 6 (SENP6) [AID2599, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
View
18
[SID7973370]
Single concentration confirmation of uHTS for inhibitors of Sentrin-specific protease 6 (SENP6) using a Luminescent assay [AID488915, Type: screening]SUMO-1-specific protease [Homo sapiens] [gi:6166485]
View
19
[SID7973370]
Primary Cell-based High Throughput Screening assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) [AID522, Type: screening]steroidogenic factor 1 [Homo sapiens] [gi:20070193]
View
20
[SID7973370]
Cycloheximide Counterscreen for Small Molecule Inhibitors of Shiga Toxin [AID2314, Type: screening]shiga toxin 1 variant A subunit [Escherichia coli O157:H7] [gi:32400299]
View