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AC1NSIQR (CID 5310346) - Compound BioActivity Data
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BioActivity Outcomes:
Probe(1)
 
 
Active(33)
 
 
Inactive(871)
 
 
Inconclusive(31)
 
 
Unspecified(7)
 
 
Top Targets:
7TM GPCR Srx(28)
 
 
 
7TM GPCR Srsx(21)
 
 
TRP 2(20)
 
 
 
NACHT(16)
 
 
 
 
alkPPc(14)
 
 
BioAssay Types:
Screening(618)
 
 
 
 
 
Confirmatory(283)
 
 
 
 
 
Literature(11)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(169)
 
 
 
 
 
IC50(76)
 
 
 
EC50(14)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 867    Data Row: 943   Total Pages: 48   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87225488]
Summary assay for the identification of compounds that inhibit NOD1 [AID1575, Type: summary]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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2
[SID7970927]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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3
[SID87225488]
IC50_Mean 0.986SAR analysis of compounds that inhibit NOD1 - Set 2 [AID2466, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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4
[SID89650212]
IC50_Mean 1.36SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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5
[SID89650203]
IC50_Mean 1.8SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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6
[SID87225488]
IC50_Mean 1.81SAR analysis of compounds that inhibit NOD1 revised [AID2333, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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7
[SID87225488]
IC50 3.43SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]interleukin-8 precursor [Homo sapiens] [gi:10834978]
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8
[SID87225488]
IC50_Mean 4.18SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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9
[SID7970927]
EC50 6.37uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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10
[SID89650212]
IC50_Mean 7.97SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
View
11
[SID87225488]
IC50_Mean 8.49SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2 [AID2483, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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12
[SID89650203]
IC50_Mean 10.6SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
View
13
[SID87225488]
IC50 14.43SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2 [AID2793, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
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14
[SID87225488]
IC50_Mean 16.9SAR analysis of compounds that inhibit NOD2 revised [AID2334, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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15
[SID89650212]
IC50_Mean 18.2SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 [AID2801, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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16
[SID7970927]
Potency 44.6684qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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17
[SID7970927]
Allosteric Modulators of D1 Receptors: Dose-dependent Assay [AID858, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
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18
[SID7970927]
CYP2C9 Assay [AID777, Type: screening]cytochrome P450 2C9 precursor [Homo sapiens] [gi:13699818]
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19
[SID7970927]
High Content Assay for Compounds that inhibit the Assembly of the Perinucleolar Compartment [AID2417, Type: screening]polypyrimidine tract-binding protein 1 isoform a [Homo sapiens] [gi:4506243]
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20
[SID7970927]
EC50 uHTS luminescence assay for the identification of compounds that inhibit NOD2 [AID1566, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 isoform 1 [Homo sapiens] [gi:11545912]
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