AC1NSIQR (CID 5310346) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Probe(1)
 
 
Active(33)
 
 
Inactive(771)
 
 
Inconclusive(25)
 
 
Unspecified(7)
 
 
Top Targets:
7TM GPCR Srx(23)
 
 
 
TRP 2(20)
 
 
 
alkPPc(14)
 
 
Bcl-2 like(11)
 
 
7TM GPCR Srsx(10)
 
 
BioAssay Types:
Screening(550)
 
 
 
 
 
Confirmatory(252)
 
 
 
 
 
Literature(5)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(147)
 
 
 
 
 
IC50(71)
 
 
 
EC50(14)
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 833    Data Row: 837   Total Pages: 17   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID87225488]
 Summary assay for the identification of compounds that inhibit NOD1 [AID1575, Type: summary]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
2
[SID87225488]
 Summary assay for the identification of compounds that inhibit NOD1 [AID1575, Type: summary]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
3
[SID7970927]
Potency 0.9285Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
View
4
[SID87225488]
IC50 0.986SAR analysis of compounds that inhibit NOD1 - Set 2 [AID2466, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
5
[SID87225488]
IC50 0.986SAR analysis of compounds that inhibit NOD1 - Set 2 [AID2466, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
6
[SID89650212]
IC50 1.36SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
7
[SID89650212]
IC50 1.36SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
8
[SID89650203]
IC50 1.8SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
9
[SID89650203]
IC50 1.8SAR analysis of compounds that inhibit NOD1 - Set 3 [AID2798, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
10
[SID87225488]
IC50 1.81SAR analysis of compounds that inhibit NOD1 revised [AID2333, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
11
[SID87225488]
IC50 1.81SAR analysis of compounds that inhibit NOD1 revised [AID2333, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
12
[SID87225488]
IC50 3.43SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
13
[SID87225488]
IC50 3.43SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
14
[SID87225488]
IC50 3.43SAR analysis of GM-Tri-DAP induced IL-8 secretion in MCF-7/NOD1 cells - Set 2 [AID2505, Type: confirmatory]IL8 gene product [Homo sapiens] [gi:10834978]
View
15
[SID87225488]
IC50 4.18SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
16
[SID87225488]
IC50 4.18SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
17
[SID87225488]
IC50 4.18SAR analysis of compounds that inhibit NOD2 - Set 2 [AID2475, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
18
[SID7970927]
EC50 6.37uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
19
[SID7970927]
EC50 6.37uHTS luminescence assay for the identification of compounds that inhibit NOD1 [AID1578, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
20
[SID89650212]
IC50 7.97SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
21
[SID89650212]
IC50 7.97SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
22
[SID89650212]
IC50 7.97SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
23
[SID87225488]
IC50 8.49SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2 [AID2483, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
24
[SID87225488]
IC50 8.49SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 2 [AID2483, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
25
[SID89650203]
IC50 10.6SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
26
[SID89650203]
IC50 10.6SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
27
[SID89650203]
IC50 10.6SAR analysis of compounds that inhibit NOD2 - Set 3 [AID2799, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
28
[SID87225488]
IC50 14.43SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2 [AID2793, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
29
[SID87225488]
IC50 14.43SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2 [AID2793, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 1 [Homo sapiens] [gi:5174617]
View
30
[SID87225488]
IC50 16.9SAR analysis of compounds that inhibit NOD2 revised [AID2334, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
31
[SID87225488]
IC50 16.9SAR analysis of compounds that inhibit NOD2 revised [AID2334, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
32
[SID87225488]
IC50 16.9SAR analysis of compounds that inhibit NOD2 revised [AID2334, Type: confirmatory]nucleotide-binding oligomerization domain-containing protein 2 [Homo sapiens] [gi:11545912]
View
33
[SID89650212]
IC50 18.2SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 [AID2801, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
34
[SID89650212]
IC50 18.2SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3 [AID2801, Type: confirmatory]TNF gene product [Homo sapiens] [gi:25952111]
View
35
[SID7970927]
Potency 44.6684qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
View
36
[SID7970927]
 Screening for Modulators of Post-Golgi Transport, Control Strain [AID738, Type: screening]
View
37
[SID7970927]
 Allosteric Modulators of D1 Receptors: Primary Screen [AID641, Type: screening]
View
38
[SID7970927]
 Allosteric Modulators of D1 Receptors: Confirmation Screen [AID642, Type: other]
View
39
[SID7970927]
 Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Counterscreen with HEK cells [AID1716, Type: other]
View
40
[SID7970927]
 Identification of Novel Modulators of Cl- dependent Transport Process via HTS: Counterscreen 2 with HEK cells [AID1718, Type: other]
View
41
[SID7970927]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
42
[SID7970927]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
43
[SID7970927]
 CYP2C9 Assay [AID777, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 9 [Homo sapiens] [gi:13699818]
View
44
[SID7970927]
 CYP2C19 Assay [AID778, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
View
45
[SID7970927]
 CYP2C19 Assay [AID778, Type: screening]cytochrome P450, family 2, subfamily C, polypeptide 19 [Homo sapiens] [gi:4503219]
View
46
[SID7970927]
 Allosteric Modulators of D1 Receptors: Dose-dependent Assay [AID858, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
View
47
[SID7970927]
 Allosteric Modulators of D1 Receptors: Dose-dependent Assay [AID858, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
View
48
[SID7970927]
 Allosteric Modulators of D1 Receptors: Dose-dependent Assay [AID858, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
View
49
[SID7970927]
 Allosteric Modulators of D1 Receptors: Dose-dependent Assay [AID858, Type: confirmatory]dopamine D1 receptor [Homo sapiens] [gi:299681]
View
50
[SID7970927]
 Parallel artificial membrane permeability assay at pH 7.4 [AID624339, Type: other]
View