Bookmark and Share
3-hydroxy-2-(5-methylpyridin-2-yl)-3H-isoindol-1-one (CID 5308351) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(35)
 
 
Inactive(473)
 
 
Inconclusive(14)
 
 
Top Targets:
7tm 4(24)
 
 
Bcl-2 like(12)
 
 
alkPPc(10)
 
 
Tryp SPc(8)
 
 
NR LBD PPAR(6)
 
 
BioAssay Types:
Screening(331)
 
 
 
 
Confirmatory(176)
 
 
 
 
Literature(2)
 
 
Summary(1)
 
 
BioActivity Types:
Potency(102)
 
 
 
 
IC50(40)
 
 
 
EC50(13)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 489    Data Row: 522   Total Pages: 27   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID7966646]
Potency 0.2818qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
View
2
[SID7966646]
Potency 0.5623qHTS Assay for Enhancers of SMN2 Splice Variant Expression [AID1458, Type: confirmatory]survival motor neuron protein isoform d [Homo sapiens] [gi:10937869]
View
3
[SID7966646]
Potency 1.5101qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
4
[SID7966646]
EC50 1.738Luminescence Cell-Based Dose Confirmation HTS to Identify Inhibitors of Platelet Dense Granule Release [AID1889, Type: confirmatory]
View
5
[SID7966646]
Potency 2.0596qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
View
6
[SID7966646]
Potency 3.6626qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
7
[SID7966646]
Potency 3.9811qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature [AID924, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
View
8
[SID7966646]
Potency 4.4668Counterscreen for Luciferase (Kinase-Glo TM) Inhibition [AID1379, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
View
9
[SID7966646]
Potency 5.0119qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature [AID902, Type: confirmatory]cellular tumor antigen p53 isoform a [Homo sapiens] [gi:120407068]
View
10
[SID7966646]
IC50 5.983Dose response cell-based assay to measure STAT3 inhibition [AID1399, Type: confirmatory]STAT3, partial [Homo sapiens] [gi:13272532]
View
11
[SID7966646]
Potency 6.3096qHTS Assay for Inhibitors of Firefly Luciferase [AID411, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
12
[SID7966646]
Potency 6.5064Secondary Assay for Luciferase (Kinase-Glo TM) Inhibition Counterscreen [AID2530, Type: confirmatory]luciferase [Photuris pennsylvanica] [gi:1669525]
View
13
[SID7966646]
EC50 6.564Luminescence Biochemical Dose Response HTS to Identify Inhibitors of Luciferase [AID1891, Type: confirmatory]
View
14
[SID7966646]
Potency 7.0795qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
View
15
[SID7966646]
Potency 7.0795qHTS Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK) [AID1721, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
16
[SID7966646]
EC50 8.296Luminescence Cell-Based Dose Confirmation HTS to Identify Compounds Cytotoxic to BJeLR RAS-Dependent Fibroblast [AID1936, Type: confirmatory]
View
17
[SID7966646]
EC50 8.32Luminescence Cell-Based Dose Response HTS to Identify Compounds Cytotoxic to BJ-TERT RAS-Independent Fibroblast [AID1933, Type: confirmatory]
View
18
[SID7966646]
Potency 11.2202qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase [AID1634, Type: confirmatory]pyruvate kinase PKM isoform a [Homo sapiens] [gi:33286418]
View
19
[SID7966646]
Potency 18.3375Confirmation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK) [AID2559, Type: confirmatory]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View
20
[SID7966646]
qHTS Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK): Summary [AID2266, Type: summary]pyruvate kinase [Leishmania mexicana mexicana] [gi:290753097]
View