cl-cob-III-194 (CID 52940465) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Probe(2)
 
 
Active(2)
 
 
Inactive(6)
 
 
BioAssay Types:
Confirmatory(8)
 
 
 
Summary(2)
 
 
BioActivity Types:
EC50(4)
 
 
 
IC50(4)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 9    Data Row: 10   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123083137]
 Summary assay for the identification of small molecule activators of the apoptotic arm of the Unfolded Protein response [AID449771, Type: summary]
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2
[SID134228465]
 Summary assay for the identification of small molecule activators of the apoptotic arm of the Unfolded Protein response [AID449771, Type: summary]
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3
[SID123083137]
EC50 0.739SAR analysis of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay - Set 2 [AID588594, Type: confirmatory]
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4
[SID134228465]
EC50 0.785SAR analysis of small molecule activators of the apoptotic arm of the Unfolded Protein response via a luminescent-based reporter assay - Set 3 [AID602434, Type: confirmatory]
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5
[SID123083137]
IC50 66.8SAR analysis of cytotoxicity in CHO-CHOP cells after 24 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein Response [AID588556, Type: confirmatory]
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6
[SID123083137]
IC50 80SAR analysis of cytotoxicity in the CHO-CHOP cells after 6 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein response [AID588557, Type: confirmatory]
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7
[SID123083137]
IC50 80SAR analysis of cytotoxicity in CHO-XBP1 cells after 24 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein response [AID588558, Type: confirmatory]
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8
[SID123083137]
IC50 80SAR analysis of cytotoxicity in CHO-XBP1 cells following 6 hours of exposure to small molecule activators of the apoptotic arm of the Unfolded Protein response [AID588570, Type: confirmatory]
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9
[SID123083137]
EC50 80SAR analysis counterscreen of small molecule activators of the apoptotic arm of the Unfolded Protein Response via a luminescent-based reporter assay - Set 2 [AID588582, Type: confirmatory]
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10
[SID134228465]
EC50 80SAR analysis counterscreen of small molecule activators of the apoptotic arm of the Unfolded Protein Response via a luminescent-based reporter assay - Set 3 [AID602416, Type: confirmatory]
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