Bookmark and Share
CHEMBL1765957 (CID 52937356) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(11)
 
 
Inactive(1)
 
 
Unspecified(3)
 
 
Top Targets:
NR LBD Lrh-1(7)
 
 
 
 
NR LBD SF-1(7)
 
 
 
BioAssay Types:
Literature(15)
 
 
 
 
BioActivity Types:
EC50(2)
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 15    Data Row: 15   Total Pages: 1   
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID131280925]
EC50 0.31623Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay relative to control [AID593529, Type: Literature]Steroidogenic factor 1 [gi:3121738]
View
2
[SID131280925]
EC50 1.25893Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay relative to control [AID593528, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View
3
[SID131280925]
Agonist activity at human LRH-1 ligand binding domain at 100 uM with Coomassie blue staining by PAGE method [AID593534, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View
4
[SID131280925]
Agonist activity human LRH-1 in HEK293 cells assessed as increase in SHP mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593614, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View
5
[SID131280925]
Agonist activity human LRH-1 in HEK293 cells assessed as increase in StAR mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593615, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View
6
[SID131280925]
Agonist activity human LRH-1 in HEK293 cells assessed as increase in GOS2 mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593617, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View
7
[SID131280925]
Displacement of dipalmitoyl phosphatidylinositol 4,5-bisphosphate from mouse SF-1 ligand binding domain at 1 uM after 16 hrs with Coomassie blue staining by PAGE method [AID593522, Type: Literature]Steroidogenic factor 1 [gi:341942103]
View
8
[SID131280925]
Agonist activity at mouse SF-1 expressed in HEK293 cells assessed as increase in SHP mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593537, Type: Literature]Steroidogenic factor 1 [gi:341942103]
View
9
[SID131280925]
Agonist activity at mouse SF-1 expressed in HEK293 cells assessed as increase in StAR mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593538, Type: Literature]Steroidogenic factor 1 [gi:341942103]
View
10
[SID131280925]
Agonist activity at mouse SF-1 expressed in HEK293 cells assessed as increase in GOS2 mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593539, Type: Literature]Steroidogenic factor 1 [gi:341942103]
View
11
[SID131280925]
Agonist activity at mouse SF-1 expressed in HEK293 cells assessed as increase in MeOx1 mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593613, Type: Literature]Steroidogenic factor 1 [gi:341942103]
View
12
[SID131280925]
Solubility of the compound [AID593530, Type: Literature]
View
13
[SID131280925]
Agonist activity at human LRH-1 receptor assessed as TIF2 737-757 peptide recruitment by TR-FRET assay [AID593526, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View
14
[SID131280925]
Agonist activity at human SF-1 assessed as DAX1 1-23 peptide recruitment by TR-FRET assay [AID593527, Type: Literature]Steroidogenic factor 1 [gi:3121738]
View
15
[SID131280925]
Agonist activity human LRH-1 in HEK293 cells assessed as increase in MeOx1 mRNA levels at 10 uM after 24 hrs by RT-qPCR method [AID593616, Type: Literature]Nuclear receptor subfamily 5 group A member 2 [gi:7676156]
View