VU0453125-1 (CID 52914884) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(2)
 
 
Top Targets:
KCNQ channel(2)
 
 
BioAssay Types:
Confirmatory(2)
 
 
BioActivity Types:
IC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 2    Data Row: 2   Total Pages: 1   
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123051004]
IC50 0.21SAR analysis for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay, CRC2 [AID588426, Type: confirmatory]Kcnq2 gene product [Rattus norvegicus] [gi:18959272]
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2
[SID123051004]
IC50 0.21SAR analysis for compounds that inhibit KCNQ2 potassium channels on automated electrophysiological assay, CRC2 [AID588426, Type: confirmatory]Kcnq2 gene product [Rattus norvegicus] [gi:18959272]
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3
[SID123051004]
IC50 29Dose response assay of SAR compounds for the identification of selective inhibitors of KCNQ2 potassium channels in the KCNQ1 expressing cells on automated patch clamp [AID588425, Type: confirmatory]KCNQ1 gene product [Homo sapiens] [gi:32479527]
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