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2-amino-5,6-dihydro-3H-purine-6-thiol (CID 5284626) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(188)
 
 
Inactive(148)
 
 
Inconclusive(76)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
globin(4)
 
 
 
HSD10-like SD..(4)
 
 
 
NR LBD TR(4)
 
 
P53(3)
 
 
 
BioAssay Types:
Confirmatory(180)
 
 
 
 
Literature(63)
 
 
 
 
BioActivity Types:
Potency(143)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 180    Data Row: 416   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389526]
Potency 0.3162Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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2
[SID17389526]
Potency 1.4382S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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3
[SID17389526]
Potency 1.5849Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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4
[SID17389526]
Potency 1.9953Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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5
[SID17389526]
Potency 1.9953Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus [AID910, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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6
[SID17389526]
Potency 2.8184qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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7
[SID17389526]
Potency 3.1623Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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8
[SID17389526]
Potency 3.1623Cell Viability - LYMP2-025 [AID976, Type: confirmatory]
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9
[SID17389526]
Potency 3.9781S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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10
[SID17389526]
Potency 5.0119Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 705 locus [AID930, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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11
[SID17389526]
Potency-Replicate_1 5.0119qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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12
[SID17389526]
Potency 6.3096Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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13
[SID17389526]
Potency 7.0795qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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14
[SID17389526]
Potency 7.5686Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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15
[SID17389526]
Potency 7.9433Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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16
[SID17389526]
Potency 7.9433Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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17
[SID17389526]
Potency 7.9433Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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18
[SID17389526]
Potency 10Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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19
[SID17389526]
Potency 10Cell Viability - LYMP1-002 - Assay at 24 hr [AID993, Type: confirmatory]
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20
[SID17389526]
Potency 10Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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21
[SID17389526]
Potency 10Cell Viability - LYMP2-023 [AID975, Type: confirmatory]
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22
[SID17389526]
Potency 12.5893Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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23
[SID17389526]
Potency 12.5893Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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24
[SID17389526]
Potency 12.5893Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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25
[SID17389526]
Potency 12.5893Cell Viability - LYMP2-022 [AID987, Type: confirmatory]
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26
[SID17389526]
Potency 12.5893Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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27
[SID17389526]
Potency 12.5893Cell Viability - LYMP2-026 [AID989, Type: confirmatory]
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28
[SID17389526]
Potency 12.5893Cell Viability - LYMP1-002 - Assay at 16 hr [AID948, Type: confirmatory]
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29
[SID17389526]
Potency 15.8489Cell Viability - LYMP2-007 [AID979, Type: confirmatory]
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30
[SID17389526]
Potency 15.8489Cell Viability - LYMP2-009 [AID968, Type: confirmatory]
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31
[SID17389526]
Potency 15.8489Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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32
[SID17389526]
Potency 15.8489Cell Viability - LYMP2-014 [AID983, Type: confirmatory]
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33
[SID17389526]
Potency 19.9526Cell Viability - LYMP2-011 [AID969, Type: confirmatory]
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34
[SID17389526]
Potency 19.9526Cell Viability - LYMP2-013 [AID970, Type: confirmatory]
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35
[SID17389526]
Potency 25.1189qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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36
[SID17389526]
Potency 33.4915qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway [AID651741, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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37
[SID17389526]
Potency 56.2341qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase) [AID1490, Type: confirmatory]phosphopantetheinyl transferase [Bacillus subtilis] [gi:10954339]
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38
[SID17389526]
Potency 66.8242qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion [AID651758, Type: confirmatory]interleukin 8 [Homo sapiens] [gi:186368]
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39
[SID17389526]
Cell Viability - NIH 3T3 [AID541, Type: confirmatory]
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40
[SID17389526]
Cell Viability - H-4-II-E [AID543, Type: confirmatory]
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41
[SID17389526]
Cell Viability - SH-SY5Y [AID544, Type: confirmatory]
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42
[SID17389526]
Cellular Toxicity (caspase-3) H-4-II-E [AID663, Type: confirmatory]
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43
[SID17389526]
Cell Viability - Mesenchymal [AID546, Type: confirmatory]
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44
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_27, Type: other]
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45
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_1, Type: other]
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46
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_2, Type: other]
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47
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_3, Type: other]
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48
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_17, Type: other]
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49
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_18, Type: other]
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50
[SID17389526]
Cell Viability Profiling of Human Lymphoblast Cell Lines [AID588812_19, Type: other]
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