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2-amino-5,6-dihydro-3H-purine-6-thiol (CID 5284626) - Compound BioActivity Data
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BioActivity Outcomes:
Active(188)
 
 
Inactive(149)
 
 
Inconclusive(76)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
globin(4)
 
 
 
HSD10-like SD..(4)
 
 
 
NR LBD TR(4)
 
 
NR LBD VDR(3)
 
 
 
BioAssay Types:
Confirmatory(180)
 
 
 
 
Literature(64)
 
 
 
 
BioActivity Types:
Potency(144)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 180    Data Row: 417   Total Pages: 21   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389526]
Potency 0.3162Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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2
[SID17389526]
Potency 1.4382S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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3
[SID17389526]
Potency 1.5849Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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4
[SID17389526]
Potency 1.9953Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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5
[SID17389526]
Potency 1.9953Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus [AID910, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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6
[SID17389526]
Potency 2.8184qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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7
[SID17389526]
Potency 3.1623Cell Viability - LYMP2-025 [AID976, Type: confirmatory]
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8
[SID17389526]
Potency 3.1623Cell Viability - LYMP2-008 [AID980, Type: confirmatory]
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9
[SID17389526]
Potency 3.9781S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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10
[SID17389526]
Potency 5.0119Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 705 locus [AID930, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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11
[SID17389526]
Potency-Replicate_1 5.0119qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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12
[SID17389526]
Potency 6.3096Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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13
[SID17389526]
Potency 7.0795qHTS assay for small molecule antagonists of glucocorticoid receptor signaling [AID588533, Type: confirmatory]glucocorticoid receptor [Homo sapiens] [gi:311348376]
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14
[SID17389526]
Potency 7.5686Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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15
[SID17389526]
Potency 7.9433Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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16
[SID17389526]
Potency 7.9433Cell Viability - LYMP2-018 [AID985, Type: confirmatory]
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17
[SID17389526]
Potency 7.9433Cell Viability - LYMP2-012 [AID982, Type: confirmatory]
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18
[SID17389526]
Potency 10Cell Viability - LYMP1-002 - Assay at 24 hr [AID993, Type: confirmatory]
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19
[SID17389526]
Potency 10Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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20
[SID17389526]
Potency 10Cell Viability - LYMP2-019 [AID973, Type: confirmatory]
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