mercury(2+) dichloride (CID 5284416) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(220)
 
 
Inactive(85)
 
 
Inconclusive(104)
 
 
Unspecified(7)
 
 
Top Targets:
NR LBD PPAR(5)
 
 
 
globin(4)
 
 
 
NR LBD TR(4)
 
 
 
P53(3)
 
 
 
NR LBD VDR(3)
 
 
 
BioAssay Types:
Confirmatory(171)
 
 
 
 
Literature(64)
 
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(135)
 
 
 
 
IC50(2)
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 185    Data Row: 416   Total Pages: 9   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389835]
Potency 0.0126qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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2
[SID17389835]
Potency 0.0126qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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3
[SID17389835]
Potency 0.1qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 1 [Homo sapiens] [gi:31542939]
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4
[SID17389835]
Potency 0.1qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 1 [Homo sapiens] [gi:31542939]
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5
[SID17389835]
Potency 0.1qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD+] isoform 1 [Homo sapiens] [gi:31542939]
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6
[SID17389835]
Potency 0.1259qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
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7
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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8
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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9
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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10
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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11
[SID17389835]
Potency 0.2512qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta- Hydroxysteroid Dehydrogenase Type 10) Bound [gi:122921310]
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12
[SID17389835]
Potency 0.2512Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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13
[SID17389835]
Potency 0.3162Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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14
[SID144204702]
Potency 0.335qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]
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15
[SID17389835]
Potency 0.3981Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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16
[SID17389835]
Potency 0.3981Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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17
[SID17389835]
Potency 0.5012Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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18
[SID144204702]
Potency 0.7499qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]
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19
[SID17389835]
Potency 0.7943qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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20
[SID17389835]
Potency 0.7943Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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21
[SID17389835]
Potency 0.7943Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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22
[SID17389835]
Potency 0.8087S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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23
[SID17389835]
Potency 1Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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24
[SID17389835]
Potency 1Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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25
[SID17389835]
Potency 1.0591qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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26
[SID17389835]
Potency 1.0591qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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27
[SID17389835]
Potency 1.0591qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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28
[SID17389835]
Potency 1.0591qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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29
[SID17389835]
Potency 1.0591qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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30
[SID17389835]
Potency 1.2589qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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31
[SID17389835]
Potency 1.2589Cell Viability - LYMP1-002 - Assay at 24 hr [AID993, Type: confirmatory]
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32
[SID17389835]
Potency 1.5849Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
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33
[SID17389835]
Potency 2.1331Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation [AID504832, Type: confirmatory]
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34
[SID17389835]
Potency 2.3934Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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35
[SID17389835]
Potency 2.5119qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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36
[SID17389835]
Potency 2.5119qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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37
[SID17389835]
Potency 2.5119qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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38
[SID17389835]
Potency 2.5119qHTS assay for small molecule antagonists of estrogen receptor alpha signaling [AID588513, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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39
[SID17389835]
Potency 2.5119Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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40
[SID17389835]
Potency 2.5119Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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41
[SID17389835]
Potency 2.5119Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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42
[SID17389835]
Potency 2.5119Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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43
[SID17389835]
Potency 2.5575S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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44
[SID17389835]
Potency 3.1599S16 Schwann cell PMP22 intronic element beta-lactamase assay [AID624044, Type: confirmatory]Pmp22 gene product [Rattus norvegicus] [gi:8393992]
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45
[SID17389835]
Potency 3.1623Cell Viability - LYMP1-002 - Assay at 40 hr [AID994, Type: confirmatory]
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46
[SID17389835]
Potency 3.1623Cell Viability - LYMP2-020 [AID986, Type: confirmatory]
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47
[SID17389835]
Potency 3.9811Inhibitors of USP1/UAF1: Pilot qHTS [AID504865, Type: confirmatory]USP1 protein [Homo sapiens] [gi:118600387]
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48
[SID17389835]
Potency 3.9811qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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49
[SID17389835]
Potency 3.9811qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP) [AID1688, Type: confirmatory]huntingtin [Homo sapiens] [gi:90903231]
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50
[SID17389835]
Potency 5.0119qHTS Assay for Inhibitors of 12-hLO (12-human lipoxygenase) [AID1452, Type: confirmatory]arachidonate 12-lipoxygenase, 12S-type [Homo sapiens] [gi:154426292]
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