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Mercuric Chloride (CID 5284416) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(312)
 
 
Inactive(135)
 
 
Inconclusive(206)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD GR(14)
 
 
 
 
NR LBD TR(13)
 
 
 
 
BioAssay Types:
Confirmatory(352)
 
 
 
 
Literature(63)
 
 
 
 
 
Summary(63)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(364)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 276    Data Row: 657   Total Pages: 14   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389835]
Potency 0.0126qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase [Homo sapiens] [gi:1832253]
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2
[SID17389835]
Potency 0.1qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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3
[SID17389835]
Potency 0.1259qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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4
[SID17389835]
Potency 0.1259qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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5
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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6
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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7
[SID144210809]
Potency-Replicate_1 0.1933qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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8
[SID144210809]
Potency-Replicate_1 0.1933qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144210809]
Potency-Replicate_1 0.2169qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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10
[SID144210809]
Potency-Replicate_1 0.2434qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
11
[SID17389835]
Potency 0.2512qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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12
[SID17389835]
Potency 0.2512qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
View
13
[SID17389835]
Potency 0.2512Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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14
[SID17389835]
Potency 0.3162Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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15
[SID144204702]
Potency 0.335qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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16
[SID144210809]
Potency-Replicate_1 0.3857qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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17
[SID17389835]
Potency 0.3981Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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18
[SID17389835]
Potency 0.3981Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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19
[SID17389835]
Potency 0.5012Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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20
[SID144204702]
Potency 0.7499qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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21
[SID144209457]
Potency-Replicate_1 0.7727qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
View
22
[SID17389835]
Potency 0.7943qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2) [AID881, Type: confirmatory]Arachidonate 15-lipoxygenase B [gi:317373425]
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23
[SID17389835]
Potency 0.7943Cell Viability - LYMP2-003 [AID965, Type: confirmatory]
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24
[SID17389835]
Potency 0.7943Cell Viability - LYMP2-001 [AID921, Type: confirmatory]
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25
[SID17389835]
Potency 0.8087S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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26
[SID144204702]
Potency-Replicate_1 0.8413qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
27
[SID144204702]
Potency-Replicate_1 0.8413qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
View
28
[SID144210809]
Potency-Replicate_1 0.977qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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29
[SID17389835]
Potency 1Cell Viability - LYMP1-003 - Assay at 40 hr [AID964, Type: confirmatory]
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30
[SID17389835]
Potency 1Cell Viability - LYMP2-017 [AID972, Type: confirmatory]
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31
[SID17389835]
Potency 1.0591qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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32
[SID144209457]
Potency-Replicate_1 1.0815qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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33
[SID144210809]
Potency-Replicate_1 1.0962qHTS assay to identify small molecule agonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743224, Type: confirmatory]
View
34
[SID144209457]
Potency-Replicate_1 1.2135qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
View
35
[SID144209457]
Potency-Replicate_1 1.2247qHTS assay to identify small molecule antagonists of the vitamin D receptor (VDR) signaling pathway - cell viability counter screen [AID743225, Type: confirmatory]
View
36
[SID17389835]
Potency 1.2589qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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37
[SID17389835]
Potency 1.2589Cell Viability - LYMP1-002 - Assay at 24 hr [AID993, Type: confirmatory]
View
38
[SID144204702]
Potency-Replicate_1 1.3333qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
39
[SID144209457]
Potency-Replicate_1 1.3616qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
View
40
[SID144209457]
Potency-Replicate_1 1.3616qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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41
[SID144209457]
Potency-Replicate_1 1.3616qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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42
[SID144209457]
Potency-Replicate_1 1.5418qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
View
43
[SID17389835]
Potency 1.5849Cell Viability - LYMP2-021 [AID974, Type: confirmatory]
View
44
[SID144204702]
Potency-Replicate_1 1.6785qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
View
45
[SID17389835]
Potency-Replicate_1 1.6785qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
View
46
[SID144209457]
Potency-Replicate_1 1.7299qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743211, Type: confirmatory]
View
47
[SID144210809]
Potency-Replicate_1 1.7374qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway - cell viability counter screen [AID743213, Type: confirmatory]
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48
[SID144209457]
Potency-Replicate_1 1.9233qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
View
49
[SID144204702]
ATAD5 Potency (uM) 1.99496qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
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50
[SID144204702]
Potency-Replicate_1 2.1132qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
View