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Mercuric Chloride (CID 5284416) - Compound BioActivity Data
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BioActivity Outcomes:
Active(314)
 
 
Inactive(138)
 
 
Inconclusive(203)
 
 
Unspecified(4)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
 
 
NR LBD ER(23)
 
 
 
 
NR LBD AR(23)
 
 
 
 
NR LBD GR(14)
 
 
 
 
NR LBD TR(13)
 
 
 
 
BioAssay Types:
Confirmatory(353)
 
 
 
 
Literature(64)
 
 
 
 
 
Summary(63)
 
 
 
 
Screening(2)
 
 
BioActivity Types:
Potency(366)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 277    Data Row: 659   Total Pages: 33   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID17389835]
Potency 0.0126qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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2
[SID17389835]
Potency 0.1qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase) [AID894, Type: confirmatory]15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 [Homo sapiens] [gi:31542939]
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3
[SID17389835]
Potency 0.1259qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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4
[SID17389835]
Potency 0.1259qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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5
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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6
[SID17389835]
Potency 0.1413qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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7
[SID144210809]
Potency-Replicate_1 0.1933qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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8
[SID144210809]
Potency-Replicate_1 0.1933qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway [AID743065, Type: confirmatory]thyroid hormone receptor beta isoform 2 [Rattus norvegicus] [gi:399498506]
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9
[SID144210809]
Potency-Replicate_1 0.2169qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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10
[SID144210809]
Potency-Replicate_1 0.2434qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signaling pathway - cell viability counter screen [AID743064, Type: confirmatory]
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11
[SID17389835]
Potency 0.2512qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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12
[SID17389835]
Potency 0.2512qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II) [AID886, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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13
[SID17389835]
Potency 0.2512Cell Viability - LYMP2-004 [AID966, Type: confirmatory]
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14
[SID17389835]
Potency 0.3162Cell Viability - LYMP2-010 [AID981, Type: confirmatory]
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15
[SID144204702]
Potency 0.335qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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16
[SID144210809]
Potency-Replicate_1 0.3857qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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17
[SID17389835]
Potency 0.3981Confirmation and Secondary Assay for Modulators of Hemoglobin Beta Chain Splicing at IVS2 654 locus: Cytotoxicity [AID931, Type: confirmatory]hemoglobin subunit beta [Homo sapiens] [gi:4504349]
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18
[SID17389835]
Potency 0.3981Cell Viability - LYMP2-024 [AID988, Type: confirmatory]
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19
[SID17389835]
Potency 0.5012Cell Viability - LYMP2-005 [AID967, Type: confirmatory]
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20
[SID144204702]
Potency 0.7499qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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