Calcifediol (CID 5283731) - BioAssay Data Summary for Compound
.
BioActivity Outcomes:
Active(17)
 
 
Inactive(81)
 
 
Inconclusive(42)
 
 
Unspecified(6)
 
 
Top Targets:
NR LBD ROR li..(4)
 
 
 
 
Menin(4)
 
 
NR LBD VDR(3)
 
 
 
DUF3652(3)
 
 
 
HELICc(3)
 
 
BioAssay Types:
Literature(72)
 
 
 
 
 
Confirmatory(63)
 
 
 
 
Screening(5)
 
 
BioActivity Types:
Potency(60)
 
 
 
 
SAR
Target summary
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 76    Data Row: 146   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID50110817]
Potency 10.5931A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. [AID624296, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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2
[SID50110817]
Potency 11.2202VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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3
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_26, Type: Literature]
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4
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_4, Type: Literature]
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5
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_11, Type: Literature]
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6
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_19, Type: Literature]
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7
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_20, Type: Literature]
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8
[SID48415681]
 DSSTox (FDAMDD) FDA Maximum (Recommended) Daily Dose Database [AID1195, Type: other]
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9
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_32, Type: Literature]
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10
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_46, Type: Literature]
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11
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_52, Type: Literature]
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12
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_53, Type: Literature]
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13
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_54, Type: Literature]
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14
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_56, Type: Literature]
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15
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_57, Type: Literature]
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16
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_60, Type: Literature]
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17
[SID103279820]
 Inhibition of Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as down regulation of Gli1 at 0.5 to 5 uM after 24 hrs by RT-PCR analysis [AID647370, Type: Literature]
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18
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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19
[SID103279820]
 Compound was tested for the backward reaction of conversion of vitamin D to previtaminD [AID25537, Type: Literature]
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20
[SID103279820]
 Compound was tested for rate constant for the forward reaction of isomerization of previtamin D to vitamin D [AID25549, Type: Literature]
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21
[SID103279820]
 Compound was evaluated for chick Vasoactive intestinal peptide receptor relative competitive indices (relative to alpha, 25-(OH2)-D3) [AID216929, Type: Literature]
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22
[SID103279820]
 Keq (k1/1-k) for the transformation of vitamin D to previtamin D [AID228114, Type: Literature]
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23
[SID103279820]
 Activation of VDR in mouse C3H10T1/2 cells assessed as up-regulation of CYP24A1 after 24 hrs by RT-PCR analysis relative to control [AID647368, Type: Literature]Vitamin D3 receptor [gi:342187016]
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24
[SID26754888]
Potency VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
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25
[SID26754888]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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26
[SID26754888]
Potency qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium [AID1457, Type: confirmatory]Inositol monophosphatase [gi:44888968]
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27
[SID99302259]
 A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis [AID540299, Type: Literature]naphthoate synthase [Mycobacterium tuberculosis H37Rv] [gi:15607688]
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28
[SID50110817]
Potency qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase: hit validation [AID492961, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei] [gi:72386991]
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29
[SID99300741]
 A screen for compounds that inhibit the bacterial siderophore biosynthetic enzyme BasE [AID485350, Type: screening]enterobactin synthase subunit E [Acinetobacter baumannii ATCC 17978] [gi:126642418]
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30
[SID99300741]
 A screen for compounds that modulate the activity of the Staphylococcus aureus MgrA protein [AID602314, Type: other]MarR family regulatory protein [Staphylococcus aureus subsp. aureus str. Newman] [gi:151220867]
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31
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_22, Type: Literature]
View
32
[SID50110817]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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33
[SID50110817]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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34
[SID50110817]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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35
[SID50110817]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
36
[SID26754888]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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37
[SID26754888]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
38
[SID26754888]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
View
39
[SID26754888]
Potency Inhibitors of the vitamin D receptor (VDR): qHTS [AID504847, Type: confirmatory]vitamin D3 receptor isoform VDRA [Homo sapiens] [gi:63054845]
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40
[SID50110817]
Potency Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation [AID504834, Type: confirmatory]
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41
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_59, Type: Literature]
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42
[SID104046490]
 Screening small molecules to find regulators of human embryonic stem cell survival. [AID493140, Type: screening]
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43
[SID50110817]
Potency A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]GMNN gene product [Homo sapiens] [gi:7705682]
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44
[SID50110817]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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45
[SID50110817]
Potency qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
View
46
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_12, Type: Literature]
View
47
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_14, Type: Literature]
View
48
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_5, Type: Literature]
View
49
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_2, Type: Literature]
View
50
[SID50110817]
 qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749_9, Type: Literature]
View