Bookmark and Share
tranilast (CID 5282230) - Compound BioActivity Data
.
BioActivity Outcomes:
Active(65)
 
 
Inactive(1261)
 
 
Inconclusive(109)
 
 
Unspecified(331)
 
 
Top Targets:
7TM GPCR Srx(58)
 
 
 
 
7TM GPCR Srsx(40)
 
 
 
alkPPc(20)
 
 
Bcl-2 like(20)
 
 
Tryp SPc(17)
 
 
 
 
BioAssay Types:
Screening(725)
 
 
 
 
Confirmatory(672)
 
 
 
 
 
Literature(114)
 
 
 
 
 
Summary(16)
 
 
 
 
BioActivity Types:
Potency(446)
 
 
 
 
 
IC50(200)
 
 
 
 
EC50(18)
 
 
AC50(7)
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 1307    Data Row: 1766   Total Pages: 89   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID855567]
Potency 0.151qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
2
[SID85231347]
Potency 0.1811Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
3
[SID26719641]
Potency 0.3013qHTS profiling assay for firefly luciferase inhibitor/activator using purifed enzyme and Km concentrations of substrates (counterscreen for miR-21 project) [AID588342, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
View
4
[SID56422140]
AC50_uM 0.587Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition Measured in Cell-Based System Using Plate Reader - 7011-01_Antagonist_Dose_CherryPick_Activity_Set2 [AID743343, Type: confirmatory]
View
5
[SID56422140]
AC50_uM 0.594LGR2:Counterscreen with MC4R Measured in Cell-Based System Using Plate Reader - 7011-02_Antagonist_Dose_CherryPick_Activity [AID743444, Type: confirmatory]MSH [Drosophila melanogaster] [gi:1098680]
View
6
[SID26719641]
Potency 0.631qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
7
[SID855567]
Potency 0.8913qHTS Assay for Rab9 Promoter Activators [AID485297, Type: confirmatory]ras-related protein Rab-9A [Homo sapiens] [gi:4759012]
View
8
[SID144204387]
ATAD5 Potency (uM) 0.943918qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5: Summary [AID720516, Type: summary]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
9
[SID50103918]
Potency 1.122qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
10
[SID144204387]
Potency-Replicate_1 1.1883qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cells expressing luciferase-tagged ATAD5 [AID651632, Type: confirmatory]ATPase family AAA domain-containing protein 5 [gi:296439460]
View
11
[SID26719641]
Potency 1.2589VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
12
[SID90341124]
Potency 1.299qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
13
[SID855567]
Potency 1.4125qHTS Assay for NPC1 Promoter Activators [AID485313, Type: confirmatory]Niemann-Pick C1 protein precursor [Homo sapiens] [gi:255652944]
View
14
[SID90341124]
Potency 1.4575qHTS for inhibitors of binding or entry into cells for Marburg Virus [AID540276, Type: confirmatory]gene 4 small orf - Marburg virus [gi:420597]
View
15
[SID90341124]
Potency 1.6353Validation screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID493106, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
View
16
[SID50103918]
Potency 1.9953qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View
17
[SID50103918]
Potency 2.8184qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID540256, Type: confirmatory]
View
18
[SID50103918]
Potency 2.8184Validation screen for inhibitors of Lassa infection [AID463096, Type: confirmatory]
View
19
[SID144204387]
Potency-Replicate_1 3.3491qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
View
20
[SID855567]
Potency 3.5481qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma [Mus musculus] [gi:188536040]
View