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BioActivity Data for Compound coenzyme Q10 (CID 5281915)

BioActivity Outcomes:
Active(3)
 
 
Inactive(269)
 
 
Inconclusive(6)
 
 
Unspecified(11)
 
 
Top Targets:
NR LBD ER(14)
 
 
NR LBD AR(14)
 
 
 
NR LBD TR(8)
 
 
NR LBD GR(8)
 
 
PLDc mTdp1 2(5)
 
 
BioAssay Types:
Confirmatory(156)
 
 
 
 
Literature(85)
 
 
 
Summary(30)
 
 
Screening(9)
 
 
BioAssay Categories:
In vitro(2)
 
 
In vivo(9)
 
 
 
Biochemical(1)
 
 
Toxicity(12)
 
 
 
ADME(6)
 
 
Cell-based(3)
 
 
 
BioActivity Types:
Potency(178)
 
 
 
 
Data download

Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 157    Data Row: 289   Total Pages: 15   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID29215368]
Potency 0.6424S16 Schwann cell PMP22 intronic element firefly luciferase assay [AID624032, Type: confirmatory]peripheral myelin protein 22 [Rattus norvegicus] [gi:8393992]
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2
[SID558940]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Human Mammary Carcinoma MX-1 Xenograft (intrarenal inoculation) in NU/NU Swiss (nude) mice [AID296, Type: other]
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3
[SID558940]
NCI In Vivo Anticancer Drug Screen. Data for tumor model Colon Carcinoma 38 (subcutaneous) in B6D2F1 (BDF1) mice [AID212, Type: other]
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4
[SID103635587]
GI50 220Growth inhibition of human FRDA primary patient fibroblasts after 48 hrs by calcein-AM-based cell viability assay [AID642427, Type: Literature]
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5
[SID29215368]
qHTS profiling for inhibitors of Plasmodium falciparum proliferation [AID504749, Type: Literature]
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6
[SID103635587]
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977602, Type: Literature]
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7
[SID103635587]
Termiticidal activity against Coptotermes formosanus placed on 1 % wt/wt compound treated filter paper assessed as termite mortality measured 21 days post compound exposure [AID1091094, Type: Literature]
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8
[SID103635587]
Termiticidal activity against Coptotermes formosanus placed on 1 % wt/wt compound treated filter paper assessed as termite mortality measured 11 days post compound exposure [AID1091095, Type: Literature]
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9
[SID103635587]
Termiticidal activity against Coptotermes formosanus placed on 1 % wt/wt compound treated filter paper assessed as termite mortality measured 3 days post compound exposure [AID1091096, Type: Literature]
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10
[SID103635587]
Antifeedant activity against Coptotermes formosanus placed on 1 % wt/wt compound treated filter paper assessed as filter paper consumption measured 21 days post compound exposure (Rvb = 85 +/- 15.1 mg) [AID1091127, Type: Literature]
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11
[SID103635587]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans [AID588211, Type: Literature]
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12
[SID103635587]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents [AID588212, Type: Literature]
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13
[SID103635587]
Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents [AID588213, Type: Literature]
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14
[SID103635587]
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM [AID977599, Type: Literature]
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15
[SID144205213]
Potency-Replicate_1 3.3491qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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16
[SID144206945]
Potency-Replicate_1 qHTS assay to identify aromatase inhibitors - cell viability counter screen [AID743084, Type: confirmatory]
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17
[SID29215368]
Potency S16 Schwann cell viability assay (CellTiter-Glo assay) [AID624031, Type: confirmatory]
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18
[SID29215368]
Potency Biochemical firefly luciferase enzyme assay for NPC [AID624030, Type: confirmatory]Luciferase [Photinus pyralis] [gi:160794]
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19
[SID144205213]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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20
[SID144206945]
Potency qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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